Abstract 5540: Tumor phenotypic plasticity and resistance to immune-mediated cytotoxicity in models of castration resistant prostate cancer

• Published in: Cancer research (Chicago, Ill.) Vol. 82; no. 12_Supplement; p. 5540
• Main Authors: Dahut, Madeline, Fousek, Kristen, Horn, Lucas, Qin, Haiyan, Schlom, Jeffrey, Palena, Claudia
• Format: Journal Article
• Language: English
• Published: 15.06.2022

Abstract Androgen receptor (AR)-targeted therapies are routinely used to treat prostate cancer, including the use of next-generation hormonal therapies such as abiraterone or enzalutamide. Although these therapies are initially effective, a significant proportion of patients exhibit resistance to tr...