Abstract 3992: Modular ddPCR assay design for highly sensitive single nucleotide variant detection

• Published in: Cancer research (Chicago, Ill.) Vol. 82; no. 12_Supplement; p. 3992
• Main Authors: Heine, Sarah, Beams, Ashley, Riccitelli, Nathan, Tangri, Shabnam
• Format: Journal Article
• Language: English
• Published: 15.06.2022

Abstract Introduction: Single-nucleotide variants (SNVs) are key drivers of both oncogenesis and emergent resistance to targeted therapies. Although high-throughput Identification of SNVs can be achieved with Next Generation Sequencing (NGS) technologies, the cost is significant, and proportional to...