Abstract 5095: Statistical modeling of transcriptional regulatory states in single-cell RNA-Seq data of tumor and infiltrated immune cells

• Published in: Cancer research (Chicago, Ill.) Vol. 79; no. 13_Supplement; p. 5095
• Main Authors: Wan, Changlin, Chang, Wennan, Lu, Xiaoyu, Sun, Yifan, So, Kaman, Cao, Sha, Lu, Xiongbin, Zhang, Chi
• Format: Journal Article
• Language: English
• Published: 01.07.2019

Single-cell RNA-seq of tumor tissue has greatly strengthened our understanding of tumor development as well as the heterogeneous tissue micro-environment. Many models are dedicated to detect deferentially expressed genes among single cells of different conditions, or to discover (novel) sub-cell typ...