Abstract 436: Prediction of aggressive disease in metastatic castration-resistant prostate cancer: The role of very small nuclear circulating tumor cells

• Published in: Cancer research (Chicago, Ill.) Vol. 79; no. 13_Supplement; p. 436
• Main Authors: Chen, Pin-Jung, Jan, Yu Jen, Teng, Pai-Chi, Chen, Jie-Fu, Cheng, Shirley, Yao, Nu, Reis-Sobreiro, Mariana, Lozano, Amber, Gomez, Amy, Tseng, Hsian-Rong, Freeman, Michael, Posadas, Edwin
• Format: Journal Article
• Language: English
• Published: 01.07.2019

Background: Circulating tumor cells (CTCs) have arisen as a contemporary noninvasive prognostic biomarker for prostate cancer (PC). Previously, a subgroup of PC CTCs, with particularly small nuclei (<8.54 μm), were found to be correlated with poor prognosis and the emergence of visceral metastase...