Abstract 3682: Synergistic immunostimulatory effects and therapeutic benefit of combined histone deacetylase and bromodomain inhibition in non-small cell lung cancer

• Published in: Cancer research (Chicago, Ill.) Vol. 77; no. 13_Supplement; p. 3682
• Main Authors: Adeegbe, Dennis O., Liu, Yan, Lizotte, Patrick, Kamihara, Yusuke, Awad, Mark, Barbie, David, Ritz, Jerome, Jones, Simon, Quayle, Steven, Hammerman, Peter, Wong, Kwok-Kin
• Format: Journal Article
• Language: English
• Published: 01.07.2017

Abstract Effective therapies for non-small cell lung cancer (NSCLC) remain challenging despite an increasingly comprehensive understanding of somatically altered oncogenic pathways. It is now clear that therapeutic agents with potential to impact the tumor immune microenvironment potentiate immune-o...