Abstract 3571: Precise somatic mutation prediction in the absence of matching normal DNA

• Published in: Cancer research (Chicago, Ill.) Vol. 77; no. 13_Supplement; p. 3571
• Main Authors: Kalatskaya, Irina, Trinh, Quang, Spears, Melanie, Bartlett, John, Stein, Lincoln
• Format: Journal Article
• Language: English
• Published: 01.07.2017

Accurate identification of somatic mutations is an essential first step for many cancer studies. It is usually done by comparing the genome of the tumour to the reference genome sequence derived from a normal tissue taken from the same donor. However, there are a number of possible scenarios in whic...