Abstract 3782: NEDD9 promotes cell invasion through modulation of Arf6-dependent endocytic recycling

• Published in: Cancer research (Chicago, Ill.) Vol. 73; no. 8_Supplement; p. 3782
• Main Authors: Loskutov, Yuriy, McLaughlin, Sarah, Kozyulina, Polina, Kozyreva, Varvara, Ice, Ryan, Rajulapati, Anuradha, Culp, Mark, Wysolmerski, Robert, Ivanov, Alexey, Weed, Scott, Pugacheva, Elena
• Format: Journal Article
• Language: English
• Published: 15.04.2013

Abstract The adaptor protein, NEDD9, is an established pro-metastatic trigger in several cancers but the molecular mechanisms behind NEDD9-driven invasion remain unclear. Here we show that expression of NEDD9 protein tightly correlates with the transition of breast cancer to invasive stages. Overexp...