Abstract 850: 32H2, a new diagnostic tool for HER2 CTFs

• Published in: Cancer research (Chicago, Ill.) Vol. 70; no. 8_Supplement; p. 850
• Main Authors: Palau, Josep L. Parra, Peg, Vicente, Escorihuela, Marta, Mancilla, Sandra, Arribas, Joaquín
• Format: Journal Article
• Language: English
• Published: 15.04.2010

Abstract The tyrosine kinase receptor HER2 belongs to the Epidermal Growth Factor Receptor (EGFR) family and is amplified in 30% of breast cancer patients. These patients are currently treated with Herceptin (Trastuzumab), a monoclonal antibody against the extracellular domain of HER2. A group of HE...