Abstract 5107: HDL and sphingosine-1-phosphate activate signal transducer and activator of transcription 3 in prostate cancer DU145 cells via ERK1/2 and S1P receptors

• Published in: Cancer research (Chicago, Ill.) Vol. 70; no. 8_Supplement; p. 5107
• Main Authors: Sekine, Yoshitaka, Suzuki, Kazuhiro, Remaley, Alan T.
• Format: Journal Article
• Language: English
• Published: 15.04.2010

Abstract (a) Introduction and Objective: Signal transducer and activator of transcription 3 (Stat3) has been implicated in the promotion of migration, invasion and growth of prostate cancer cells. Recently, HDL, which transports the bioactive lipid sphingosine-1-phosphate (S1P), was reported to acti...