Abstract 3930: Radiation-induced dicentrics: Tracking by parallel sequencing

• Published in: Cancer research (Chicago, Ill.) Vol. 70; no. 8_Supplement; p. 3930
• Main Authors: Vaughan, Andrew T.M, Shih, Shyh-Jen, Singh, Sheetal, Do, To Uyen
• Format: Journal Article
• Language: English
• Published: 15.04.2010

Abstract Radiation and cytotoxic drugs exert much of their lethal effects by creating aberrations, such as dicentrics, that are lethal at a subsequent mitosis. Their accurate enumeration in experimental and clinical settings would provide valuable information on the efficacy of radiation and radiati...