The enriched expression of aquaporin-2 in the renal inner medulla is mediated by increased chromatin accessibility

• Published in: Physiology (Bethesda, Md.) Vol. 39; no. S1
• Main Authors: Engel, Kristina, Nerger, Katrin, Chernyakov, Dmitry, Edemir, Bayram
• Format: Journal Article
• Language: English
• Published: 01.05.2024

Abstract only Introduction: The osmotic gradient between renal cortex (CTX) and renal inner medulla (IM) is important for the generation of a concentrated urine. In addition, the unique hypertonic environment in the IM induces a specific gene expression pattern. For example the expression of aquapor...