Transcription factor expression levels and environmental signals constrain transcription factor innovation This article is part of the Microbial Evolution collection

• Published in: Microbiology (Society for General Microbiology) Vol. 169; no. 8
• Main Authors: Shepherd, Matthew J., Reynolds, Mitchell, Pierce, Aidan P., Rice, Alan M., Taylor, Tiffany B.
• Format: Journal Article
• Language: English
• Published: 16.08.2023

Evolutionary innovation of transcription factors frequently drives phenotypic diversification and adaptation to environmental change. Transcription factors can gain or lose connections to target genes, resulting in novel regulatory responses and phenotypes. However the frequency of functional adapta...