Rapid, cost-effective DNA quantification via a visuallydetectable aggregation of superparamagnetic silicamagnetite nanoparticles

• Published in: 纳米研究：英文版 no. 5; pp. 755 - 764
• Main Author: Qian Liu Jingyi Li Hongxue Liu Ibrahim Tora Matthew S. Ide Jiwei Lu Robert J. Davis David L. Green James P. Landers
• Format: Journal Article
• Language: English
• Published: 2014
• Subjects: DNA; 二氧化硅纳米粒子; 成本效益; 溶剂热法合成; 短串联重复序列位点; 磁性纳米粒子; 纳米二氧化硅; 聚集体

DNA and silica-coated magnetic particles entangle and form visible aggregates under chaotropic conditions with a rotating magnetic field, in a manner that enables quantification of DNA by image analysis. As a means of exploring the mechanism of this DNA quantitation assay, nanoscale SiO2-coated Fe30...