Bovine lactoferrin improves bone mass and micro-structure in ovariectomized rats via OPG/RANKL/RANK pathway

• Published in: 中国药理学报：英文版 Vol. 33; no. 10; pp. 1277 - 1284
• Main Author: Jian-ming HOU Ying XUE Qing-ming LIN
• Format: Journal Article
• Language: English
• Published: 2012
• Subjects: mRNA水平; OPG; RANK; 去卵巢大鼠; 定量RT-PCR; 微结构; 牛乳铁蛋白; 骨量

Aim： Lactoferrin （LF）, an 80-kDa iron-binding glycoprotein, is a pleiotropic factor found in colostrum, milk, saliva and epithelial cells of the exocrine glands. The aim of this study was to evaluate the effects of LF on the bones in ovariectomized （Ovx） rats and to identify the pathways that mediat...