Alpha-GalCer Administration after AIIogeneic Bone Marrow Transplantation Improves Immune Reconstitution in Mice

• Published in: 中国医学科学杂志：英文版 Vol. 26; no. 2; pp. 91 - 97
• Main Author: Jing-hua Liu Li-ping DOU Li-xin Wang Li-li Wang Fan Zhou Li Yu
• Format: Journal Article
• Language: English
• Published: 2011
• Subjects: CD34; CD40; 免疫; 小鼠; 政府; 移植物抗宿主病; 胸腺微环境; 骨髓移植

Objective To explore the effect of α-galactosyleramide （α-GalCer） on immune reconstitution under acute graft-versus-host disease （aGVHD）. Methods BALB/c mice were transplanted with allogeneic C57BL/6 bone marrow cells and splenocytes （both 1 × 10^7） after receiving lethal total-body irradiation, α-G...