Effect of cholinesterase inhibitor galanthamine on circulating tumor necrosis factor alpha in rats with lipopolysaccharideinduced peritonitis

• Published in: Chinese medical journal Vol. 123; no. 13; pp. 1727 - 1730
• Main Author: LIU Zhi-hai MA Yue-feng WU Jun-song GAN Jian-xin XU Shao-wen JIANG Guan-yu
• Format: Journal Article
• Language: English
• Published: 2010
• Subjects: lip; 加兰他敏; 大鼠模型; 水平循环; 肿瘤坏死因子-α; 胆碱酯酶抑制剂; 腹膜炎; 迷走神经

Background The nervous system, through the vagus nerve and its neurotransmitter acetylcholine, can down-regulate the systemic inflammation in vivo, and recently, a role of brain cholinergic mechanisms in activating this cholinergic anti-inflammatory pathway has been indicated. Galanthamine is a chol...