Influence of the Calmodulin Antagonist EBB on Cyclin B1 and Cdc2-p34 in Human Drug-resistant Breast Cancer MCF-7/ADR Cells

• Published in: Clinical oncology and cancer research Vol. 5; no. 2; pp. 108 - 112
• Main Author: Xu Shi Yanhong Cheng Linglin Zou Dongsheng Xiong Yuan Zhou Ming Yang Dongmei Fan Xiaohua Dai Chunzheng Yang Huifang Zhu
• Format: Journal Article
• Language: English
• Published: 2008
• Subjects: 乳腺癌; 治疗方法; 细胞凋亡; 细胞周期蛋白

OBJECTIVE To investigate the influence of O-（4-ethoxyl-butyl）- berbamine （EBB） on the expression of cyclin B1 and cdc2-p34 in the human drug-resistant breast cancer MCF-7/ADR cell line. METHODS The MTT assay was used to assess the cytotoxicity of EBB. Different levels of EBB were added to different...