Receptor-mediated gene delivery using polyethylenimine （PEI） coupled with polypeptides targeting FGF receptors on cells surface

• Published in: Journal of Zhejiang University. B. Science Vol. 7; no. 11; pp. 906 - 911
• Main Author: LI Da WANG Qing-qing TANG Gu-ping HUANG Hong-liang SHEN Fen-ping LI Jing-zhong YU Hai
• Format: Journal Article
• Language: English
• Published: 2006
• Subjects: FGF受体; 基因治疗; 目标命中; 聚氮丙啶

Objective： To construct a novel kind of nonviral gene delivery vector based on polyethylenimine （PEI） conjugated with polypeptides derived from ligand FGF with high transfection efficiency and according to tumor targeting ability. Methods： The synthetic polypeptides CR16 for binding FGF receptors wa...