Identification and characterisation of somatic regulatory mutations in the breast cancer genome

• Main Author: Slaven, Neil David
• Format: Dissertation
• Language: English
• Published: Imperial College London 2022

Luminal breast cancer remains a major clinical challenge with over 2 million cases diagnosed annually. While prognosis is favourable in these patients, roughly 40% will relapse over the course of the next 20 years. Understanding the evolution of disseminated tumour cells at distal sites is critical...