Discovery of high quality molecular leads and screening collections for CNS drug targets

• Main Author: Farnaby, William
• Format: Dissertation
• Language: English
• Published: University of Dundee 2019

Diseases of the central nervous system represent an increasing area of unmet medical need. Despite high levels of investment from the pharmaceutical industry few disease modifying drugs have been discovered with the most common cause of late stage clinical failure being a lack of efficacy. In order...