Wernicke's Encephalopathy in a Nigerian with Schizophrenia

While Wernicke's encephalopathy (WE) is a well-characterized syndrome in alcoholism and malnutrition, little is written of its prevalence or presentation in patients with psychiatric illness. We present a case of a 37-year-old Nigerian male with schizophrenia and malnutrition who presented with...

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Published inAnnals of African medicine Vol. 6; no. 4
Main Authors Salawu, F, Kwajaffa, S
Format Journal Article
LanguageEnglish
Published Annals of African Medicine Society 20.03.2008
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Abstract While Wernicke's encephalopathy (WE) is a well-characterized syndrome in alcoholism and malnutrition, little is written of its prevalence or presentation in patients with psychiatric illness. We present a case of a 37-year-old Nigerian male with schizophrenia and malnutrition who presented with delirium and ophthalmoplegia. The clinical diagnosis was supported by dramatic reversal of the symptoms and signs following the administration of intravenous thiamine. Owing to the high rate of mortality and morbidity, WE should be considered in the evaluation of any patient with unexplained nystagmus, gaze palsies, gait ataxia, or confusion, especially if a condition associated with malnutrition is present. This is particularly important in psychiatric patients where the clinical history and syndrome may be obscured and treatment delayed. Bien que l'encéphalopathie de Wernicke (WE) est un syndrome bien caractéristique de l'alcoolisme et de la sous-alimentation. Il y a peu d'écrits à propos de sa fréquence ou présentation chez des patients atteints de la maladie psychiatrique. Nous pressentons un cas d'un homme nigérian âgé de 37 ans atteint de la schizophrénie et de la sous-alimentation qui s'est présenté avec delirium et ophtalmologie. Le diagnostic clinique a été appuyé par le renversement spectaculaire de symptômes et signes à la suite de l'administration intraveineuse de la thiamine. En raison de taux élevé de mortalité et de morbidité, le WE devraient être considérée dans l'évaluation de tous les patients avec une nystagmus inexpliquée, regard palsie, giat ataxie, ou la confusion surtout si une condition liée à la sous alimentation est présent. Cela est particulièrement important chez des patients psychiatriques où l'histoire clinique et syndrome peuvent être obscur et traitement retardé.
AbstractList While Wernicke's encephalopathy (WE) is a well-characterized syndrome in alcoholism and malnutrition, little is written of its prevalence or presentation in patients with psychiatric illness. We present a case of a 37-year-old Nigerian male with schizophrenia and malnutrition who presented with delirium and ophthalmoplegia. The clinical diagnosis was supported by dramatic reversal of the symptoms and signs following the administration of intravenous thiamine. Owing to the high rate of mortality and morbidity, WE should be considered in the evaluation of any patient with unexplained nystagmus, gaze palsies, gait ataxia, or confusion, especially if a condition associated with malnutrition is present. This is particularly important in psychiatric patients where the clinical history and syndrome may be obscured and treatment delayed. Bien que l'encéphalopathie de Wernicke (WE) est un syndrome bien caractéristique de l'alcoolisme et de la sous-alimentation. Il y a peu d'écrits à propos de sa fréquence ou présentation chez des patients atteints de la maladie psychiatrique. Nous pressentons un cas d'un homme nigérian âgé de 37 ans atteint de la schizophrénie et de la sous-alimentation qui s'est présenté avec delirium et ophtalmologie. Le diagnostic clinique a été appuyé par le renversement spectaculaire de symptômes et signes à la suite de l'administration intraveineuse de la thiamine. En raison de taux élevé de mortalité et de morbidité, le WE devraient être considérée dans l'évaluation de tous les patients avec une nystagmus inexpliquée, regard palsie, giat ataxie, ou la confusion surtout si une condition liée à la sous alimentation est présent. Cela est particulièrement important chez des patients psychiatriques où l'histoire clinique et syndrome peuvent être obscur et traitement retardé.
Author Kwajaffa, S
Salawu, F
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Snippet While Wernicke's encephalopathy (WE) is a well-characterized syndrome in alcoholism and malnutrition, little is written of its prevalence or presentation in...
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SubjectTerms Encéphalopathie de Wernick, schizophrénie
Wernicke's encephalopathy, schizophrenia
Title Wernicke's Encephalopathy in a Nigerian with Schizophrenia
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