Application of Kernel Method to Reveal Subtypes of TF Binding Motifs Causal Analysis of Gene Expression Data

• Published in: Regulatory Genomics pp. 42 - 51
• Main Authors: Kel, Alexander, Tikunov, Yury, Voss, Nico, Borlak, Jürgen, Wingender, Edgar
• Format: Book Chapter
• Language: English
• Published: Berlin, Heidelberg Springer Berlin Heidelberg 2005
• Series: Lecture Notes in Computer Science
• Subjects: Gene Expression Data; Gibbs Sampling; Kernel Method; Weight Kernel; Weight Matrice

Transcription factor binding sites often contain several subtypes of sequences that follow not just one but several different patterns. We developed a novel sensitive method based on kernel estimations that is able to reveal subtypes of TF binding sites. The developed method produces patterns in for...