Biselides A-E: novel polyketides from the Okinawan ascidian Didemnidae sp

Five new polyketides, biselides A (1), B (2), C (3), D (4), and E (5), were isolated from the Okinawan ascidian Didenmidae sp. Their structures were determined by spectroscopic analysis. Biselides A (1), B (2), and C (3) showed cytotoxicity against human cancer cells NCl-H460 and MDA-MB-231. (c) 200...

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Bibliographic Details
Published inTetrahedron Vol. 61; no. 27; pp. 6561 - 6567
Main Authors Teruya, T, Suenaga, K, Maruyama, S, Kurotaki, M, Kigoshi, H
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier 04.07.2005
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
NA
polyketide
OOCYDIN
marine natural product
MACROLIDES
cytotoxicity
ascidian
macrolide
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Summary:Five new polyketides, biselides A (1), B (2), C (3), D (4), and E (5), were isolated from the Okinawan ascidian Didenmidae sp. Their structures were determined by spectroscopic analysis. Biselides A (1), B (2), and C (3) showed cytotoxicity against human cancer cells NCl-H460 and MDA-MB-231. (c) 2005 Elsevier Ltd. All rights reserved.
ISSN:0040-4020
DOI:10.1016/j.tet.2005.04.052