Reduction of Particle Size of Drug Substance for Low‐Dose Drug Products

• Published in: Formulation and Analytical Development for Low‐Dose Oral Drug Products pp. 205 - 222
• Main Authors: Burcham, Christopher L, Collins, Paul C, Jarmer, Daniel J, Seibert, Kevin D
• Format: Book Chapter
• Language: English
• Published: Hoboken, NJ, USA John Wiley & Sons, Inc 22.01.2009
• Subjects: reduction of particle size of drug substance for low‐dose drug products; reduction of particle size of drug substance using crystallization technologies; Supercritical fluid crystallization (SFC)

This chapter contains sections titled: Introduction Reduction of Particle Size of Drug Substance by Milling Technologies Reduction of Particle Size of Drug Substance Using Crystallization Technologies Scale‐Up Considerations Emerging Technologies and Future Directions Acknowledgments References