Discovery of New Medicines

The drug discovery process has been built upon a well‐established paradigm of target identification followed by selection of tool compounds, hits, leads and clinical candidates. While most of the currently approved new molecular entities (NMEs) have followed this path, pressures to decrease time to...

Full description

Saved in:
Bibliographic Details
Published inThe Textbook of Pharmaceutical Medicine pp. 1 - 31
Main Author Ribeill, Yves J
Format Book Chapter
LanguageEnglish
Published Oxford, UK Blackwell Publishing Ltd 18.04.2013
Subjects
CNS
disease
drug discovery
FBDD
immune
inflammation
marketed
metabolic
orphan
strategy
virus
Online AccessGet full text

Cover

More Information
Summary:The drug discovery process has been built upon a well‐established paradigm of target identification followed by selection of tool compounds, hits, leads and clinical candidates. While most of the currently approved new molecular entities (NMEs) have followed this path, pressures to decrease time to approval, cost and clinical failures have necessitated the incorporation of new strategies in drug discovery. Chapter 1 discusses drugs discovered in the most researched areas, as well as some of the strategic shifts of the last few years.
ISBN:9780470659878
0470659874
DOI:10.1002/9781118532331.ch1