Síndrome urémico hemolítico inducido por Escherichia coli enterohemorrágica

El síndrome urémico hemolítico (SUH) se caracteriza por anemia hemolítica microangiopática, plaquetopenia y daño renal. Constituye la primera causa de insuficiencia renal aguda en la edad pediátrica y la segunda de insuficiencia renal crónica. Escherichia coli productor de toxina Shiga (STEC, por su...

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Published inArchivos argentinos de pediatría Vol. 106; no. 5; pp. 435 - 442
Main Authors Ibarra, Cristina, Goldstein, Jorge, Silberstein, Claudia, Zotta, Elsa, Belardo, Marcela, Repetto, Horacio A
Format Journal Article
LanguagePortuguese
Spanish
Published Sociedad Argentina de Pediatría 01.10.2008
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PEDIATRICS
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Abstract El síndrome urémico hemolítico (SUH) se caracteriza por anemia hemolítica microangiopática, plaquetopenia y daño renal. Constituye la primera causa de insuficiencia renal aguda en la edad pediátrica y la segunda de insuficiencia renal crónica. Escherichia coli productor de toxina Shiga (STEC, por su sigla en inglés) es el primer agente etiológico de SUH; su principal reservorio es el ganado bovino y la vía de transmisión, los alimentos contaminados. Hasta el presente no existe un tratamiento específico para disminuir la progresión del SUH. El estudio de los mecanismos por los cuales STEC infecta y la toxina Shiga induce SUH puede ayudar a desarrollar nuevas estrategias para impedir esta enfermedad.
AbstractList El síndrome urémico hemolítico (SUH) se caracteriza por anemia hemolítica microangiopática, plaquetopenia y daño renal. Constituye la primera causa de insuficiencia renal aguda en la edad pediátrica y la segunda de insuficiencia renal crónica. Escherichia coli productor de toxina Shiga (STEC, por su sigla en inglés) es el primer agente etiológico de SUH; su principal reservorio es el ganado bovino y la vía de transmisión, los alimentos contaminados. Hasta el presente no existe un tratamiento específico para disminuir la progresión del SUH. El estudio de los mecanismos por los cuales STEC infecta y la toxina Shiga induce SUH puede ayudar a desarrollar nuevas estrategias para impedir esta enfermedad.
Author Ibarra, Cristina
Goldstein, Jorge
Zotta, Elsa
Belardo, Marcela
Repetto, Horacio A
Silberstein, Claudia
AuthorAffiliation Hospital Nacional Prof. Alejandro Posadas
Universidad de Buenos Aires
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Snippet El síndrome urémico hemolítico (SUH) se caracteriza por anemia hemolítica microangiopática, plaquetopenia y daño renal. Constituye la primera causa de...
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SubjectTerms PEDIATRICS
Title Síndrome urémico hemolítico inducido por Escherichia coli enterohemorrágica
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