Microencapsulación de sustancias oleosas mediante secado por aspersión

Para administrar por vía oral compuestos oleosos como los extractos lipídicos de origen natural, los aceites esenciales volátiles y las vitaminas liposolubles, se hace necesario presentarlos en forma de cápsulas blandas. Una alternativa a esta forma de presentación es la microencapsulación, que ofre...

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Published inRevista cubana de farmacía Vol. 44; no. 3; pp. 381 - 389
Main Author López Hernández, Orestes Darío
Format Journal Article
LanguagePortuguese
Published Editorial Ciencias Médicas 01.09.2010
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Abstract Para administrar por vía oral compuestos oleosos como los extractos lipídicos de origen natural, los aceites esenciales volátiles y las vitaminas liposolubles, se hace necesario presentarlos en forma de cápsulas blandas. Una alternativa a esta forma de presentación es la microencapsulación, que ofrece una solución para modificar el estado físico y presentarlos en una forma sólida para su administración por vía oral. Esta alternativa permite enmascarar el olor y sabor desagradable de productos que van a ser administrados por vía oral, además de proteger de la oxidación a los ácidos grasos presentes. El secado por aspersión es uno de los métodos más utilizados a escala industrial para la obtención de microcápsulas. Debido a su creciente uso en la industria farmacéutica, en el presente trabajo se recopila el estado del arte en el uso de esta tecnología para la microencapsulación de sustancias oleosas.
AbstractList Para administrar por vía oral compuestos oleosos como los extractos lipídicos de origen natural, los aceites esenciales volátiles y las vitaminas liposolubles, se hace necesario presentarlos en forma de cápsulas blandas. Una alternativa a esta forma de presentación es la microencapsulación, que ofrece una solución para modificar el estado físico y presentarlos en una forma sólida para su administración por vía oral. Esta alternativa permite enmascarar el olor y sabor desagradable de productos que van a ser administrados por vía oral, además de proteger de la oxidación a los ácidos grasos presentes. El secado por aspersión es uno de los métodos más utilizados a escala industrial para la obtención de microcápsulas. Debido a su creciente uso en la industria farmacéutica, en el presente trabajo se recopila el estado del arte en el uso de esta tecnología para la microencapsulación de sustancias oleosas.
Author López Hernández, Orestes Darío
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DocumentTitleAlternate Microencapsulation of oily substances by aspersion drying
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Keywords sustancias oleosas
Microencapsulation
aspersion dry
oily substances
secado por aspersión
Microencapsulación
Language Portuguese
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References Rodríguez, M; Pedroza, R; Prado, L; Beristain, C; Vernon, E 2004; 69
Treybal, RE 1985
Soottitantawat, A; Yoshii, H; Furuta, T; Ohkawara, M; Linko, P 2003; 68
Rodríguez, R; Grosso, C 2008; 25
López, O; Menéndez, R; Nuñez, Y; Bellma, A; Tillán, J; León, R 2009
Aili, W; Yagang, Z; Bin, W 2002
Drusch, S; Serfert, Y; Van Den Heuvel, A; Schwarz, K 2006; 39
Hoegger, R 2002; 13
Minemoto, Y; Hakamata, K; Adachi, S; Matsuno, R 2002; 19
Rosenberg, M; Kopelman, T; Talmon, Y 1990; 38
García, E; Gutiérrez, S; Nolasco, H 2007
Yánez, J; Salazar, J; Montoya, L; Chaires, J; Jiménez, M; Márquez, E 2002; 21
McNamee, B; Dolores, E; O'Sullivan, M 2001; 49
Dollo, G; Le Corre, P; Guérin, A; Chevann, F; Burgot, JL; Leverge, R 2003; 19
2006
Ré, MI 2000; 27
Kolanowski, W; Jaworska, D; Weißbrodt, J; Kunz, B 2007; 84
Drusch, S 2007; 21
Perry, RH; Green, DW 1999
Yoshi Furuta, H.T; Soottitantawat, A 2001; 2
Pedroza, R; Macías, S; Vernon, E 2002; 1
Yan-li, X; Hui-ming, Z; Zhi-rong, Z 2007; 31
López, O; Márquez, T; Mayo, O; Toledo, C; Sanchez, E 2009; 28
Drusch, S; Schwarz, K 2006; 222
Goud, K; Jin Park, H 2005; 23
Loksuwan, J 2007; 21
Voigt, R 1982
Brown, GG 1966
Watanabe, Y; Fang, X; Minemoto, Y; Adachi, S; Matsuno, R 2002; 50
Drusch, S; Serfert, Y; Scampicchio, M; Schmidt-Hansberg, B; Schwarz, K 2007; 55
Habi Mat, DianL; Sudin, N; Yusoff, M 1996; 70
Jimenez, M; García, H; Beristain, C 2004; 219
Därr, A 1981
Masters, K 1991
Hogan, S; McNamee, B; Dolores, E; O'Sullivan, M 2001; 49
Bae, E; Lee, S 2002; 25
Drusch, S; Serfert, Y; Schwarz, K 2006; 108
References_xml – volume: 70
  start-page: 422
  year: 1996
  end-page: 6
  article-title: Characteris tics of Microencapsulated Palm-Based Oil as Affected by Type of Wall Material
  publication-title: J Sci Food Agric.
  contributor:
    fullname: Habi Mat, DianL; Sudin, N; Yusoff, M
– volume: 19
  start-page: 181
  issue: 1
  year: 2002
  end-page: 9
  article-title: Oxidation of linoleic acid encapsulated with gum arabic or maltodextrin by spray-drying
  publication-title: J Microencapsul.
  contributor:
    fullname: Minemoto, Y; Hakamata, K; Adachi, S; Matsuno, R
– volume: 27
  start-page: 25
  issue: 162
  year: 2000
  end-page: 9
  article-title: Microencapsulação em busca do produtos inteligentes
  publication-title: Ciência Hoje.
  contributor:
    fullname: Ré, MI
– year: 2006
  publication-title: Information Spray dryers
– volume: 21
  start-page: 928
  year: 2007
  end-page: 35
  article-title: Characteristics of microencapsulated b-carotene formed by spray drying with modified tapioca starch, native tapioca starch and maltodextrin
  publication-title: Food Hydrocolloids.
  contributor:
    fullname: Loksuwan, J
– volume: 219
  start-page: 588
  issue: 6
  year: 2004
  end-page: 92
  article-title: Spray-drying microencapsulation and oxidative stability of conjugated linoleic acid
  publication-title: Eur Food Res Technol.
  contributor:
    fullname: Jimenez, M; García, H; Beristain, C
– volume: 13
  start-page: 16
  year: 2002
  article-title: Büchi training papers spray drying
  publication-title: Büchi Labortechnik AG.
  contributor:
    fullname: Hoegger, R
– volume: 25
  start-page: 13
  issue: 1
  year: 2008
  end-page: 20
  article-title: Cashew gum microencapsulation protects the aroma of coffee extracts
  publication-title: J Microencapsul.
  contributor:
    fullname: Rodríguez, R; Grosso, C
– volume: 108
  start-page: 501
  year: 2006
  end-page: 12
  article-title: Microencapsulation of fish oil with n-octenylsuccinate-derivatised starch: Flow properties and oxidative stability
  publication-title: Eur J Lipid Sci Technol.
  contributor:
    fullname: Drusch, S; Serfert, Y; Schwarz, K
– volume: 50
  start-page: 3984
  year: 2002
  end-page: 7
  article-title: Supresive effect of saturated acyl´L-ascorbate on the oxidation of linoleic acid encapsulated with maltodextrin or gum Arabic by spray drying
  publication-title: J Agric Food Chem.
  contributor:
    fullname: Watanabe, Y; Fang, X; Minemoto, Y; Adachi, S; Matsuno, R
– start-page: 151
  year: 1981
  publication-title: Tecnología farmacéutica
  contributor:
    fullname: Därr, A
– volume: 84
  start-page: 37
  year: 2007
  end-page: 45
  article-title: Sensory Assessment of Microencapsulated Fish Oil Powder
  publication-title: J Am Oil Chem Soc.
  contributor:
    fullname: Kolanowski, W; Jaworska, D; Weißbrodt, J; Kunz, B
– volume: 21
  start-page: 1223
  year: 2007
  end-page: 8
  article-title: Sugar beet pectin: A novel emulsifying wall component for microencapsulation of lipophilic food ingredients by spray-drying
  publication-title: Food Hydrocolloids.
  contributor:
    fullname: Drusch, S
– volume: 19
  start-page: 273_80
  year: 2003
  article-title: Spray-dried redispersible oil-in-water emulsion to improve oral bioavailability of poorly soluble drugs
  publication-title: Eur J Pharm Sci.
  contributor:
    fullname: Dollo, G; Le Corre, P; Guérin, A; Chevann, F; Burgot, JL; Leverge, R
– volume: 31
  start-page: 68
  issue: 1
  year: 2007
  end-page: 80
  article-title: Effect of relative humidity on retention and stability of vitamin A microencapsulated by spray drying
  publication-title: J Food Biochem.
  contributor:
    fullname: Yan-li, X; Hui-ming, Z; Zhi-rong, Z
– year: 2006
  publication-title: Secado por aspersión y su uso en la encapsulación
– volume: 222
  start-page: 155
  year: 2006
  end-page: 64
  article-title: Microencapsulation properties of two different types of n-octenylsuccinate-derivatised starch
  publication-title: Eur Food Res Technol.
  contributor:
    fullname: Drusch, S; Schwarz, K
– year: 2007
  publication-title: Desarrollo de bebidas lácteas enriquecidas con ácidos grasos: Tecnología Láctea Latinoamericana
  contributor:
    fullname: García, E; Gutiérrez, S; Nolasco, H
– volume: 25
  start-page: 1
  issue: 1
  year: 2002
  end-page: 12
  article-title: Microencapsulation of avocado oil by spray drying using whey protein and maltodextrin
  publication-title: J Microencapsul.
  contributor:
    fullname: Bae, E; Lee, S
– year: 2002
  publication-title: Conjugate linoleic acid or conjugate linoleate microcapsule
  contributor:
    fullname: Aili, W; Yagang, Z; Bin, W
– volume: 23
  start-page: 1361
  year: 2005
  end-page: 94
  article-title: Recent Developments in Microencapsulation of Food Ingredients: Dry Technol
  publication-title: .
  contributor:
    fullname: Goud, K; Jin Park, H
– year: 1991
  publication-title: Spray Drying Handbook
  contributor:
    fullname: Masters, K
– volume: 49
  start-page: 3385
  year: 2001
  end-page: 8
  article-title: Effect of partial replacement of gum arabic with carbohydrates on its microencapsulation properties
  publication-title: J Agric Food Chem.
  contributor:
    fullname: McNamee, B; Dolores, E; O'Sullivan, M
– volume: 28
  start-page: 628
  issue: 4
  year: 2009
  end-page: 32 b
  article-title: Características del aceite de semillas de Cucurbita pepo L: Microencapsulado mediante secado por aspersión con maltodextrina y goma arábiga
  publication-title: Lat Am J Pharm.
  contributor:
    fullname: López, O; Márquez, T; Mayo, O; Toledo, C; Sanchez, E
– volume: 49
  start-page: 1934
  year: 2001
  end-page: 8
  article-title: Microencapsulating properties of sodium caseinate
  publication-title: J Agric Food Chem.
  contributor:
    fullname: Hogan, S; McNamee, B; Dolores, E; O'Sullivan, M
– volume: 21
  start-page: 313
  year: 2002
  end-page: 9
  article-title: Aplicaciones biotecnológicas de la microencapsulación
  publication-title: Avance y Perspectiva.
  contributor:
    fullname: Yánez, J; Salazar, J; Montoya, L; Chaires, J; Jiménez, M; Márquez, E
– year: 2009
  publication-title: Solicitud de patente internacional publicada: WO 2009/071033 A1
  contributor:
    fullname: López, O; Menéndez, R; Nuñez, Y; Bellma, A; Tillán, J; León, R
– volume: 38
  start-page: 1288
  year: 1990
  end-page: 94
  article-title: Factors Affecting Retention in Spray-Drying Microencapsulation of Volatile Materials
  publication-title: J Agric Food Chem.
  contributor:
    fullname: Rosenberg, M; Kopelman, T; Talmon, Y
– volume: 1
  start-page: 37
  year: 2002
  end-page: 44
  article-title: Oil thermo-oxidative stability and surface oil determination of biopolymer microcapsules
  publication-title: Rev Mex Ing Quím.
  contributor:
    fullname: Pedroza, R; Macías, S; Vernon, E
– volume: 2
  start-page: 55
  year: 2001
  end-page: 61
  article-title: Microencapsulation of food flavors by spray drying
  publication-title: Inno. Food Sci Emerg Technol.
  contributor:
    fullname: Yoshi Furuta, H.T; Soottitantawat, A
– volume: 39
  start-page: 807
  year: 2006
  end-page: 15
  article-title: Physicochemical characterization and oxidative stability of Wsh oil encapsulated in an amorphous matrix containing trehalose
  publication-title: Food Res Int.
  contributor:
    fullname: Drusch, S; Serfert, Y; Van Den Heuvel, A; Schwarz, K
– volume: 69
  start-page: 351
  issue: 7
  year: 2004
  end-page: 9
  article-title: Microencapsulation by spray drying of multiple emulsions containing carotenoids
  publication-title: J Food Sci.
  contributor:
    fullname: Rodríguez, M; Pedroza, R; Prado, L; Beristain, C; Vernon, E
– volume: 55
  start-page: 11044
  year: 2007
  end-page: 51
  article-title: Impact of Physicochemical Characteristics on the Oxidative Stability of Fish Oil Microencapsulated by Spray-Drying
  publication-title: J Agric Food Chem.
  contributor:
    fullname: Drusch, S; Serfert, Y; Scampicchio, M; Schmidt-Hansberg, B; Schwarz, K
– year: 1999
  publication-title: Chemical Engineers Handbook
  contributor:
    fullname: Perry, RH; Green, DW
– volume: 68
  start-page: 2256
  issue: 7
  year: 2003
  end-page: 62
  article-title: Microencapsulation by Spray Drying: Influence of emulsion size on the retention of volatile compounds
  publication-title: J Food Sci.
  contributor:
    fullname: Soottitantawat, A; Yoshii, H; Furuta, T; Ohkawara, M; Linko, P
– year: 1985
  publication-title: Operaciones con transferencia de masa
  contributor:
    fullname: Treybal, RE
– start-page: 64
  year: 1982
  end-page: 5
  publication-title: Tratado de tecnología farmacéutica
  contributor:
    fullname: Voigt, R
– year: 1966
  publication-title: Operaciones básicas de la ingeniería química
  contributor:
    fullname: Brown, GG
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Title Microencapsulación de sustancias oleosas mediante secado por aspersión
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