导管泵辅助模式对心血管和冠状动脉血流动力学的影响
R318; 通过构建基于经皮导管泵辅助模式的心血管及冠状动脉系统的集中参数模型,采用数值仿真方法研究冠状动脉狭窄对患者血流动力学的影响,以及导管泵对冠状动脉系统的影响.研究结果表明:不同的导管泵辅助模式均可有效提高左主干狭窄合并心力衰竭患者心血管的心输出量,帮助左心室卸载;导管泵的变转速辅助模式和定转速辅助模式均可有效提高狭窄情况下冠状动脉的血液灌注量和冠脉血压,维持血流动力学的稳定;当左主干狭窄程度分别为60％和80％时,变转速辅助模式可分别辅助提高左主干血流量38.1％和47.4％,且均高于定转速辅助模式;相较于定转速辅助模式,变转速辅助模式在提高心输出量、狭窄冠脉的血流量以及提高血流的搏...
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| Published in | 江苏大学学报（自然科学版） Vol. 44; no. 6; pp. 710 - 718 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | Chinese |
| Published |
江苏大学电气信息工程学院,江苏镇江 212013
2023
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1671-7775 |
| DOI | 10.3969/j.issn.1671-7775.2023.06.013 |
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| Abstract | R318; 通过构建基于经皮导管泵辅助模式的心血管及冠状动脉系统的集中参数模型,采用数值仿真方法研究冠状动脉狭窄对患者血流动力学的影响,以及导管泵对冠状动脉系统的影响.研究结果表明:不同的导管泵辅助模式均可有效提高左主干狭窄合并心力衰竭患者心血管的心输出量,帮助左心室卸载;导管泵的变转速辅助模式和定转速辅助模式均可有效提高狭窄情况下冠状动脉的血液灌注量和冠脉血压,维持血流动力学的稳定;当左主干狭窄程度分别为60％和80％时,变转速辅助模式可分别辅助提高左主干血流量38.1％和47.4％,且均高于定转速辅助模式;相较于定转速辅助模式,变转速辅助模式在提高心输出量、狭窄冠脉的血流量以及提高血流的搏动性等方面,具有较明显的优势. |
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| AbstractList | R318; 通过构建基于经皮导管泵辅助模式的心血管及冠状动脉系统的集中参数模型,采用数值仿真方法研究冠状动脉狭窄对患者血流动力学的影响,以及导管泵对冠状动脉系统的影响.研究结果表明:不同的导管泵辅助模式均可有效提高左主干狭窄合并心力衰竭患者心血管的心输出量,帮助左心室卸载;导管泵的变转速辅助模式和定转速辅助模式均可有效提高狭窄情况下冠状动脉的血液灌注量和冠脉血压,维持血流动力学的稳定;当左主干狭窄程度分别为60％和80％时,变转速辅助模式可分别辅助提高左主干血流量38.1％和47.4％,且均高于定转速辅助模式;相较于定转速辅助模式,变转速辅助模式在提高心输出量、狭窄冠脉的血流量以及提高血流的搏动性等方面,具有较明显的优势. |
| Author | 张志豪 朱凤莲 徐凡 张瑶 何辰杨 王芳群 |
| AuthorAffiliation | 江苏大学电气信息工程学院,江苏镇江 212013 |
| AuthorAffiliation_xml | – name: 江苏大学电气信息工程学院,江苏镇江 212013 |
| Author_FL | ZHANG Zhihao HE Chenyang ZHANG Yao ZHU Fenglian WANG Fangqun XU Fan |
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| Author_xml | – sequence: 1 fullname: 王芳群 – sequence: 2 fullname: 张志豪 – sequence: 3 fullname: 朱凤莲 – sequence: 4 fullname: 张瑶 – sequence: 5 fullname: 徐凡 – sequence: 6 fullname: 何辰杨 |
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| DocumentTitle_FL | Effects of catheter pump auxiliary mode on cardiovascular and coronary hemodynamics |
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| Keywords | percutaneous catheter pup 集中参数模型 经皮导管泵 辅助模式 centralied parameter model coronary stenosis auxiliary mode 冠脉狭窄 hemodynamics 血流动力学 |
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| Title | 导管泵辅助模式对心血管和冠状动脉血流动力学的影响 |
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