慢性乙型肝炎临床热点问题解析

R512.62; 乙型肝炎病毒慢性感染呈世界性流行态势,如不及时治疗,可持续进展至肝硬化甚至肝细胞癌.近20年来,由于核苷(酸)类似物的上市及更新换代,在抑制乙肝病毒复制方面取得了质的飞跃,大多数慢性乙型肝炎(CHB)患者均可实现减轻肝细胞炎症及纤维化、改善生活质量、延长生存时间等目标.随着治疗时间的延长及治疗经验的积累,新的热点问题逐渐浮现,包括新型血清学标志物在临床的应用,CHB抗病毒治疗适应证的扩大、CHB治疗方案的制定以及长期预后的改善等,值得临床进一步关注....

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Published in解放军医学杂志 Vol. 48; no. 2; pp. 132 - 137
Main Authors 纪冬, 杨永平
Format Journal Article
LanguageChinese
Published 解放军总医院第五医学中心肝病医学部,北京 100039 2023
Subjects
预后
治疗
诊断
乙型肝炎,慢性
Online AccessGet full text
ISSN0577-7402
DOI10.11855/j.issn.0577-7402.2023.02.0132

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Abstract R512.62; 乙型肝炎病毒慢性感染呈世界性流行态势,如不及时治疗,可持续进展至肝硬化甚至肝细胞癌.近20年来,由于核苷(酸)类似物的上市及更新换代,在抑制乙肝病毒复制方面取得了质的飞跃,大多数慢性乙型肝炎(CHB)患者均可实现减轻肝细胞炎症及纤维化、改善生活质量、延长生存时间等目标.随着治疗时间的延长及治疗经验的积累,新的热点问题逐渐浮现,包括新型血清学标志物在临床的应用,CHB抗病毒治疗适应证的扩大、CHB治疗方案的制定以及长期预后的改善等,值得临床进一步关注.
AbstractList R512.62; 乙型肝炎病毒慢性感染呈世界性流行态势,如不及时治疗,可持续进展至肝硬化甚至肝细胞癌.近20年来,由于核苷(酸)类似物的上市及更新换代,在抑制乙肝病毒复制方面取得了质的飞跃,大多数慢性乙型肝炎(CHB)患者均可实现减轻肝细胞炎症及纤维化、改善生活质量、延长生存时间等目标.随着治疗时间的延长及治疗经验的积累,新的热点问题逐渐浮现,包括新型血清学标志物在临床的应用,CHB抗病毒治疗适应证的扩大、CHB治疗方案的制定以及长期预后的改善等,值得临床进一步关注.
Author 纪冬
杨永平
AuthorAffiliation 解放军总医院第五医学中心肝病医学部,北京 100039
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Ji Dong
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治疗
诊断
乙型肝炎,慢性
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Title 慢性乙型肝炎临床热点问题解析
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