四种营养评价方法对腰椎退行性疾病术后并发症的预测价值比较研究

R323.4; 背景 腰椎退行性疾病(LDD)术后并发症的发生与营养不良密切相关,而目前缺乏能有效、客观、全面评估LDD患者营养状态并预测术后并发症发生的营养评价方法.目的 比较术前预后营养指数(PNI)、营养控制状态评分(CONUT)、那不勒斯预后评分(NPS)和高敏改良格拉斯哥预后评分(HS-mGPS)四种营养评价方法对LDD患者术后发生并发症的预测价值,以便制定精准营养干预方案,有效预防并发症的发生.方法 选取 2021年 12 月—2022 年 7 月在中南大学湘雅医院脊柱外科确诊为LDD且接受开放手术的患者 201 例为研究对象,分别应用PNI、CONUT、NPS及HS-mGPS四种...

Full description

Saved in:
Bibliographic Details
Published in中国全科医学 Vol. 27; no. 11; pp. 1349 - 1355
Main Authors 曾藜, 王惠惠, 王晓宇, 龚渭轶, 胡纯秋
Format Journal Article
LanguageChinese
Published 410008 湖南省长沙市,中南大学湘雅医院脊柱外科%230032 安徽省合肥市,安徽医科大学公共卫生学院 15.04.2024
230032 安徽省合肥市,安徽医科大学公共卫生学院
Subjects
Online AccessGet full text

Cover

Loading…
Abstract R323.4; 背景 腰椎退行性疾病(LDD)术后并发症的发生与营养不良密切相关,而目前缺乏能有效、客观、全面评估LDD患者营养状态并预测术后并发症发生的营养评价方法.目的 比较术前预后营养指数(PNI)、营养控制状态评分(CONUT)、那不勒斯预后评分(NPS)和高敏改良格拉斯哥预后评分(HS-mGPS)四种营养评价方法对LDD患者术后发生并发症的预测价值,以便制定精准营养干预方案,有效预防并发症的发生.方法 选取 2021年 12 月—2022 年 7 月在中南大学湘雅医院脊柱外科确诊为LDD且接受开放手术的患者 201 例为研究对象,分别应用PNI、CONUT、NPS及HS-mGPS四种营养评价方法对患者进行术前营养状况评估,观察患者术后至出院并发症发生情况,并根据术后有无并发症发生分为并发症组和非并发症组,分析比较两组患者临床特征资料是否存在差异;采用受试者工作特征(ROC)曲线计算不同营养评价方法的最佳截断值,比较不同评价方法的预测效能,运用MedCalc软件进行ROC曲线下面积(AUC)比较;多因素Logistic回归模型分析不同营养评价方法与术后并发症发生的相关性.结果 术后发生并发症患者有 60 例,发生率为 29.8%.临床特征资料比较发现,并发症组与非并发症组年龄、性别、术中出血量、手术节段、PNI、CONUT及NPS评分比较,差异有统计学意义(P<0.05).ROC曲线计算PNI、CONUT、NPS、HS-mGPS预测LDD术后发生并发症的最佳截断值分别为 47.5、2 分、1 分、1 分,依据截断值将不同营养评价方法进行组内比较,结果显示,低PNI、高CONUT评分和高NPS评分与术后并发症相关(P<0.01),而高HS-mGPS评分与术后并发症无关(P=0.815).AUC结果显示CONUT与HS-mGPS(Z=4.961,P<0.000 1)、CONUT与NPS(Z=2.534,P=0.011 3)、CONUT与PNI(Z=3.455,P=0.000 6)、HS-mGPS与NPS(Z=3.349,P=0.000 8)、NPS与PNI(Z=2.025,P=0.042 9)AUC两两比较,差异均有统计学意义;HS-mGPS与PNI(Z=1.594,P=0.110 9)AUC两两比较,差异无统计学意义.多因素Logistic回归分析结果显示,CONUT(OR=2.431,95%CI=1.37
AbstractList R323.4; 背景 腰椎退行性疾病(LDD)术后并发症的发生与营养不良密切相关,而目前缺乏能有效、客观、全面评估LDD患者营养状态并预测术后并发症发生的营养评价方法.目的 比较术前预后营养指数(PNI)、营养控制状态评分(CONUT)、那不勒斯预后评分(NPS)和高敏改良格拉斯哥预后评分(HS-mGPS)四种营养评价方法对LDD患者术后发生并发症的预测价值,以便制定精准营养干预方案,有效预防并发症的发生.方法 选取 2021年 12 月—2022 年 7 月在中南大学湘雅医院脊柱外科确诊为LDD且接受开放手术的患者 201 例为研究对象,分别应用PNI、CONUT、NPS及HS-mGPS四种营养评价方法对患者进行术前营养状况评估,观察患者术后至出院并发症发生情况,并根据术后有无并发症发生分为并发症组和非并发症组,分析比较两组患者临床特征资料是否存在差异;采用受试者工作特征(ROC)曲线计算不同营养评价方法的最佳截断值,比较不同评价方法的预测效能,运用MedCalc软件进行ROC曲线下面积(AUC)比较;多因素Logistic回归模型分析不同营养评价方法与术后并发症发生的相关性.结果 术后发生并发症患者有 60 例,发生率为 29.8%.临床特征资料比较发现,并发症组与非并发症组年龄、性别、术中出血量、手术节段、PNI、CONUT及NPS评分比较,差异有统计学意义(P<0.05).ROC曲线计算PNI、CONUT、NPS、HS-mGPS预测LDD术后发生并发症的最佳截断值分别为 47.5、2 分、1 分、1 分,依据截断值将不同营养评价方法进行组内比较,结果显示,低PNI、高CONUT评分和高NPS评分与术后并发症相关(P<0.01),而高HS-mGPS评分与术后并发症无关(P=0.815).AUC结果显示CONUT与HS-mGPS(Z=4.961,P<0.000 1)、CONUT与NPS(Z=2.534,P=0.011 3)、CONUT与PNI(Z=3.455,P=0.000 6)、HS-mGPS与NPS(Z=3.349,P=0.000 8)、NPS与PNI(Z=2.025,P=0.042 9)AUC两两比较,差异均有统计学意义;HS-mGPS与PNI(Z=1.594,P=0.110 9)AUC两两比较,差异无统计学意义.多因素Logistic回归分析结果显示,CONUT(OR=2.431,95%CI=1.37
Abstract_FL Background The occurrence of postoperative complications in lumbar degenerative disease(LDD)is closely related to malnutrition,and currently there is a lack of nutritional evaluation methods that can effectively,objectively,and comprehensively assess the nutritional status of LDD patients and predict the occurrence of postoperative complications.Objective To compare the predictive value of four nutritional evaluation methods of Prognostic Nutritional Index(PNI),Controlling Nutritional Status(CONUT),Naples Prognostic Score(NPS)and High-sensitivity Modified Glasgow Prognostic Score(HS-mGPS)for postoperative complications in patients with LDD,so as to formulate a precise nutritional intervention plan and effectively prevent complications.Methods A total of 201 patients diagnosed with LDD and underwent open surgery in Spine Surgery Department of Xiangya Hospital of Central South University from December 2021 to July 2022 were selected as the study subjects,four nutritional evaluation methods of PNI,CONUT,NPS and HS-mGPS were applied to assess the preoperative nutritional status of the patients,respectively,and occurrence of postoperative complications from postoperative period to hospital discharge were observed.The patients were divided into the complication group and non-complication group according to the occurrence of postoperative complications to analyze and compare the difference in clinical characteristics between the two groups;the optimal cut-off values of different nutritional evaluation methods were calculated by plotting the receiver operating characteristic(ROC)curve,and the prediction efficiency of different evaluation methods was compared,the area under curve(AUC)was compared by using MedCalc software.Multivariate Logistic regression model was used to analyze the correlation between different nutritional evaluation methods and postoperative complications.Results Postoperative complications occurred in 60 patients with an incidence rate of 29.8%.The comparison of clinical characteristics data showed statistically significant differences in age,gender,intraoperative bleeding,surgical segment,PNI,CONUT,and NPS scores between the complication group and non-complication group(P<0.05).The optimal cut-off values of PNI,CONUT,NPS,and HS-mGPS for predicting postoperative complications of LDD were calculated by using ROC curve were 47.5,2 scores,1 score,and 1 score,respectively,and the different nutritional evaluation methods were compared within the group based on the cut-off values,showing that low PNI score,high CONUT score,and high NPS score were associated with postoperative complications(P<0.01),while high HS-mGPS score was not associated with postoperative complications(P=0.815).The comparison of AUC showed statistically significant differences between CONUT and HS-mGPS(Z=4.961,P<0.000 1),CONUT and NPS(Z=2.534,P=0.011 3),CONUT and PNI(Z=3.455,P=0.000 6),HS-mGPS and NPS(Z=3.349,P=0.000 8),NPS and PNI(Z=2.025,P=0.042 9);there was no statistically significant difference between HS-mGPS and PNI(Z=1.594,P=0.110 9).Multivariate Logistic regression analysis showed that CONUT(OR=2.431,95%CI=1.376-4.295,P=0.002),surgical segment(OR=11.924,95%CI=5.491-25.893,P<0.001)were independent influencing factors for postoperative complications after LDD.Conclusion Among the four nutritional evaluation methods used to predict postoperative complications of LDD patients,CONUT score is the most effective and can be used as an independent predictor of postoperative complications of LDD.
Author 王晓宇
曾藜
王惠惠
龚渭轶
胡纯秋
AuthorAffiliation 230032 安徽省合肥市,安徽医科大学公共卫生学院;410008 湖南省长沙市,中南大学湘雅医院脊柱外科%230032 安徽省合肥市,安徽医科大学公共卫生学院
AuthorAffiliation_xml – name: 230032 安徽省合肥市,安徽医科大学公共卫生学院;410008 湖南省长沙市,中南大学湘雅医院脊柱外科%230032 安徽省合肥市,安徽医科大学公共卫生学院
Author_FL HU Chunqiu
ZENG Li
WANG Xiaoyu
GONG Weiyi
WANG Huihui
Author_FL_xml – sequence: 1
  fullname: ZENG Li
– sequence: 2
  fullname: WANG Huihui
– sequence: 3
  fullname: WANG Xiaoyu
– sequence: 4
  fullname: GONG Weiyi
– sequence: 5
  fullname: HU Chunqiu
Author_xml – sequence: 1
  fullname: 曾藜
– sequence: 2
  fullname: 王惠惠
– sequence: 3
  fullname: 王晓宇
– sequence: 4
  fullname: 龚渭轶
– sequence: 5
  fullname: 胡纯秋
BookMark eNo9UM1Kw0AY3EMFa-1TePCUuF92t2GPUvyDghe9eCmbTVJaJUWD-HMK2OJBrRVqC9aDilI8RRArpdKnMZv0LQwoModhBmYGZg5lvLrnILQAWAcDgC7V9KrvezpgbGqcmYZuYIPomALOoOy_O4vyvl-1UkmZCYxn0U7U78eDq6T9EjXHSdj4Hn-q7ki930bhKGm-qefWNAiSx0sVDOLuJO411X0YtVvRaBhd38S98_iuMX1qqI-LNBgFXyrsJJOz-KETvw7n0Ywr9nwn_8c5tL26slVc10qbaxvF5ZLmAzaYxiUQKaUlCzbj1OSUYBc7tsAYDIlTUCxt4IIRYQkgwnUlYbYpXVmQbsHiJIcWf3uPhOcKr1Ku1Q8PvHSxfFrZ3z05Tp-gABgY-QE7K3nS
ClassificationCodes R323.4
ContentType Journal Article
Copyright Copyright © Wanfang Data Co. Ltd. All Rights Reserved.
Copyright_xml – notice: Copyright © Wanfang Data Co. Ltd. All Rights Reserved.
DBID 2B.
4A8
92I
93N
PSX
TCJ
DOI 10.12114/j.issn.1007-9572.2023.0410
DatabaseName Wanfang Data Journals - Hong Kong
WANFANG Data Centre
Wanfang Data Journals
万方数据期刊 - 香港版
China Online Journals (COJ)
China Online Journals (COJ)
DatabaseTitleList
DeliveryMethod fulltext_linktorsrc
DocumentTitle_FL Comparison of the Predictive Value of Four Nutritional Evaluation Methods for Postoperative Complications of Lumbar Degenerative Diseases
EndPage 1355
ExternalDocumentID zgqkyx202411015
GrantInformation_xml – fundername: (国家自然科学基金); (安徽省高等学校科学研究项目); 安徽医科大学公共卫生与预防医学高峰学科建设项目
  funderid: (国家自然科学基金); (安徽省高等学校科学研究项目); 安徽医科大学公共卫生与预防医学高峰学科建设项目
GroupedDBID -05
2B.
4A8
92F
92I
93N
ABJNI
ACGFS
ALMA_UNASSIGNED_HOLDINGS
CCEZO
CIEJG
CW9
GROUPED_DOAJ
PSX
TCJ
TGQ
U1G
U5O
ID FETCH-LOGICAL-s1025-9c13cccbc6d59479430f0eda0012c0c0c40cd19a53aba13affc35d7cfc6cf6b93
ISSN 1007-9572
IngestDate Thu May 29 04:06:50 EDT 2025
IsPeerReviewed true
IsScholarly true
Issue 11
Keywords 预后营养指数
术后并发症
高敏改良格拉斯哥预后评分
Lumbar degenerative disease
Naples Prognostic Score
营养评价方法
Nutritional evaluation method
那不勒斯预后评分
腰椎退行性疾病
营养控制状态评分
Prognostic Nutritional Index
Controlling Nutritional Status
Postoperative complications
High-sensitive Modified Glasgow Prognostic Score
Language Chinese
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-s1025-9c13cccbc6d59479430f0eda0012c0c0c40cd19a53aba13affc35d7cfc6cf6b93
PageCount 7
ParticipantIDs wanfang_journals_zgqkyx202411015
PublicationCentury 2000
PublicationDate 2024-04-15
PublicationDateYYYYMMDD 2024-04-15
PublicationDate_xml – month: 04
  year: 2024
  text: 2024-04-15
  day: 15
PublicationDecade 2020
PublicationTitle 中国全科医学
PublicationTitle_FL Chinese General Practice
PublicationYear 2024
Publisher 410008 湖南省长沙市,中南大学湘雅医院脊柱外科%230032 安徽省合肥市,安徽医科大学公共卫生学院
230032 安徽省合肥市,安徽医科大学公共卫生学院
Publisher_xml – name: 410008 湖南省长沙市,中南大学湘雅医院脊柱外科%230032 安徽省合肥市,安徽医科大学公共卫生学院
– name: 230032 安徽省合肥市,安徽医科大学公共卫生学院
SSID ssib007457159
ssj0058485
ssib007693709
ssib017477037
ssib007457160
ssib007457161
ssib001103591
ssib051368463
Score 2.3514392
Snippet R323.4; 背景 腰椎退行性疾病(LDD)术后并发症的发生与营养不良密切相关,而目前缺乏能有效、客观、全面评估LDD患者营养状态并预测术后并发症发生的营养评价方法.目的...
SourceID wanfang
SourceType Aggregation Database
StartPage 1349
Title 四种营养评价方法对腰椎退行性疾病术后并发症的预测价值比较研究
URI https://d.wanfangdata.com.cn/periodical/zgqkyx202411015
Volume 27
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3da9RAEA-lgvgiiorfFHSfyp3ZJJvsPiZ3OYqgTy0UX0o-mgrCibYF7dOBLT6otUJtwfqgohSfThArpdK_xtxd_wtnJrlc-iF-cOHYbGZnfzOzyc5sNruadj0IQl1FcVyJwF2tgAcuKqGKrUocGIEeJ7alaMr_rdv22IR1c1JMDg3vlmYtzc-F1WjhyO9K_seqkAd2xa9k_8GyBVPIgDTYF_7BwvD_VzZmvmDKw8N3mOswWWe-ZEpnrsBLUjDPwxy3waTFfAtPPYf5NlM28xQmPJMpIgYazJFUSsdLLriZPvMVToaAA_lwJmt4CU6hOqgU-fiUcLAgcq4hKwSmU3GBbD2b8DSY4n3irLhLwBRzDUoANyDzSlAF1uVRpcBWWQgDapQmiaxTDiSwirKfTRwAcD1XkVfPFeLKXFeIRKA4qCKBlG4xSElyeCSZRLCqNrjioFQI0UYQrl4kjiRRiimT-EOOMyBRyBykR4kzmBIx5kLkozAGTd7JvkOl-8bC1yRylEop1D1KUEeEqMsaRAXIGezpNYjGwPrRAmBVA26mfVrJCwq0s-sUOugzl8TKI6sWelLIEGyFzQRaB-FX0HB4zgch9bVr4JsA3TRG--JnUHyyRQE3ayeSOBp5ux3APVywgFIy4kEBMkPX-rcAz6V1qRQ0GNUoEecilTpnHFZXwtnXe2crS_SfUrzUF-PCmyW_jpvZetCHfAaDc4ucBqykWlRSBTObVd3KZ13vX5R9YebBvcePsCGA-4xrXBwzIEw1SkM6FI5wXCBz0H86lnDK4QOdl4YnsvMSvQ3Bw2B5PQ6hP3TQRbgguGlL2s0i8zwhlqAtiAsRjmvX-gLe-L149LliMwmaMyXPevyUdjIPiUfc7Pl2WhtauHtGu5NubHQ3X_RWPqVLO7324s-d75217c7X12l7u7f0pfNxea_V6r1_3mltdtd2u-tLnbftdGU53d5KX77qrj_tvlnc-7DY-fYMCqatH532am_3Sffdavfz1lltouGP18Yq-T4wlVmOu22riJtRFIWRHQuFO2KYeqJPxwGGapEOP0uPYq4CYQZhwM0gSSJTxE6URHaU2KEyz2nDzfvN6fPaiOJxbMowsWwVWLaIQhkoCFpjJ-ZBwhN5QRvJdTGVP-dnpw7Y-uKfSS5pJwbPiMva8NzD-ekrELvMhVepgfwCI3vxuA
linkProvider Directory of Open Access Journals
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E5%9B%9B%E7%A7%8D%E8%90%A5%E5%85%BB%E8%AF%84%E4%BB%B7%E6%96%B9%E6%B3%95%E5%AF%B9%E8%85%B0%E6%A4%8E%E9%80%80%E8%A1%8C%E6%80%A7%E7%96%BE%E7%97%85%E6%9C%AF%E5%90%8E%E5%B9%B6%E5%8F%91%E7%97%87%E7%9A%84%E9%A2%84%E6%B5%8B%E4%BB%B7%E5%80%BC%E6%AF%94%E8%BE%83%E7%A0%94%E7%A9%B6&rft.jtitle=%E4%B8%AD%E5%9B%BD%E5%85%A8%E7%A7%91%E5%8C%BB%E5%AD%A6&rft.au=%E6%9B%BE%E8%97%9C&rft.au=%E7%8E%8B%E6%83%A0%E6%83%A0&rft.au=%E7%8E%8B%E6%99%93%E5%AE%87&rft.au=%E9%BE%9A%E6%B8%AD%E8%BD%B6&rft.date=2024-04-15&rft.pub=410008+%E6%B9%96%E5%8D%97%E7%9C%81%E9%95%BF%E6%B2%99%E5%B8%82%2C%E4%B8%AD%E5%8D%97%E5%A4%A7%E5%AD%A6%E6%B9%98%E9%9B%85%E5%8C%BB%E9%99%A2%E8%84%8A%E6%9F%B1%E5%A4%96%E7%A7%91%25230032+%E5%AE%89%E5%BE%BD%E7%9C%81%E5%90%88%E8%82%A5%E5%B8%82%2C%E5%AE%89%E5%BE%BD%E5%8C%BB%E7%A7%91%E5%A4%A7%E5%AD%A6%E5%85%AC%E5%85%B1%E5%8D%AB%E7%94%9F%E5%AD%A6%E9%99%A2&rft.issn=1007-9572&rft.volume=27&rft.issue=11&rft.spage=1349&rft.epage=1355&rft_id=info:doi/10.12114%2Fj.issn.1007-9572.2023.0410&rft.externalDocID=zgqkyx202411015
thumbnail_s http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fwww.wanfangdata.com.cn%2Fimages%2FPeriodicalImages%2Fzgqkyx%2Fzgqkyx.jpg