Protective Effects of Oxymatrine on Vascular Endothelial Cells from High-Glucose-Induced Cytotoxicity by Inhibiting the Expression of A 2B Receptor

• Published in: Cellular physiology and biochemistry Vol. 45; no. 2; pp. 558 - 571
• Main Authors: Yun, Yi, Shen, Yulin, Wu, Qin, Rao, Jingan, Guan, Shu, Rao, Shenqiang, Huang, Liping, Tan, Mengxia, He, Lingkun, Liu, Lijuan, Li, Guodong, Liang, Shangdong, Xiong, Wei, Gao, Yun
• Format: Journal Article
• Language: English
• Published: Basel S. Karger AG 01.02.2018
• Subjects: Adenosine; Binding sites; Cell culture; Cell growth; Computer simulation; Diabetes; Experiments; Hyperglycemia; Inflammation; Kinases; Ligands; Proteins; China

Background/Aims: Diabetes mellitus (DM) has become an increasingly epidemic metabolic disease. Vascular endothelial cells play a key role in developing the cardiovascular complications of DM. The A2B receptor is expressed in vascular endothelial cells, and may help regulate the function of endotheli...