Basic Science and Pathogenesis

• Published in: Alzheimer's & dementia Vol. 20 Suppl 1; p. e090000
• Main Authors: Prajapati, Paresh, Geleta, Urim, Wang, Wang-Xia
• Format: Journal Article
• Language: English
• Published: United States 01.12.2024
• Subjects: Alzheimer Disease - genetics; Alzheimer Disease - metabolism; Alzheimer Disease - pathology; Animals; Brain - metabolism; Brain - pathology; Female; Inflammation; Macrophages - metabolism; Male; Mice; Mice, Knockout; Microglia - metabolism; MicroRNAs - genetics; MicroRNAs - metabolism

The characterization of intercellular communication between peripheral immune cells and the central nervous system (CNS) are essential for understanding the brain's response to aging and disease states, such as Alzheimer's disease. MicroRNAs (miRNAs) constitute a class of small non-coding...