Basic Science and Pathogenesis

• Published in: Alzheimer's & dementia Vol. 20 Suppl 1; p. e088938
• Main Authors: Kulczynska-Przybik, Agnieszka, Dulewicz, Maciej, Zetterberg, Henrik, Hanrieder, Jörg, Blennow, Kaj, Mroczko, Jan, Krawczuk, Daria, Doroszkiewicz, Julia, Borawska, Renata, Slowik, Agnieszka, Mroczko, Barbara
• Format: Journal Article
• Language: English
• Published: United States 01.12.2024
• Subjects: Aged; Alzheimer Disease - cerebrospinal fluid; Amyloid beta-Peptides - cerebrospinal fluid; Biomarkers - cerebrospinal fluid; Chemokine CX3CL1 - cerebrospinal fluid; Cognitive Dysfunction - cerebrospinal fluid; Disease Progression; Female; Humans; Male; Middle Aged; Neurogranin - cerebrospinal fluid; Peptide Fragments - cerebrospinal fluid; tau Proteins - cerebrospinal fluid

Cognitive disorders are a growing cause of morbidity and mortality worldwide. Diagnostic approaches to improve early diagnosis of cognitive disorders are constantly being sought. The pathogenesis of cognitive impairment is multifactorial and complex. It is believed that microglial activation and syn...