One-pot bottom-up fabrication of biocompatible PEGylated WS 2 nanoparticles for CT-guided photothermal therapy of tumors in vivo

• Published in: Biochemical and biophysical research communications Vol. 511; no. 3; p. 587
• Main Authors: Wang, Jiang-Tao, Zhang, Wei, Wang, Wan-Bi, Wu, Yong-Juan, Zhou, Ling, Cao, Feng
• Format: Journal Article
• Language: English
• Published: United States 09.04.2019
• Subjects: Animals; Cell Line, Tumor; Female; Hyperthermia, Induced; Mammary Neoplasms, Animal - diagnostic imaging; Mammary Neoplasms, Animal - therapy; Mice; Nanoparticles - therapeutic use; Polyethylene Glycols - therapeutic use; Theranostic Nanomedicine; Tomography, X-Ray Computed; Tungsten Compounds - therapeutic use; Nanoparticles; Photothermal therapy; Tumor; Computed tomography; WS

Tungsten disulfide (WS ), which enjoyed a good potential to be a promising clinical theranostic agent for cancer treatment, is still subject to the tedious synthesis procedure. Here, we reported a one-pot 'bottom-up' hydrothermal strategy for the fabrication of PEGylated WS nanoparticles (...