Effect of Dynamic Polyrotaxane Coating on Cytoskeletal Signaling Expression of Adhering Stem Cells and Downstream Differentiations

• Published in: Advances in Science and Technology Vol. 102; pp. 37 - 42
• Main Authors: Seo, Ji Hun, Yamaoka, Tetsuji, Kakinoki, Sachiro, Yui, Nobuhiko, Hirata, Mitsuhi
• Format: Journal Article
• Language: English
• Published: Zurich Trans Tech Publications Ltd 31.10.2016
• Subjects: Small GTPase Proteins; Stem Cell Commitment; Polyrotaxane; Molecular Mobility

The effect of molecular mobility of the supramolecular surfaces on the intracellular signaling pathway and the downstream cell functions were investigated. As a supramolecular cell culture platform, polyrotaxanes (PRXs) with a varied number of threaded host molecules were synthesized and coated on g...