Integrated imaging using MRI and 123I metaiodobenzylguanidine scintigraphy to improve sensitivity and specificity in the diagnosis of pediatric neuroblastoma

• Published in: American journal of roentgenology (1976) Vol. 181; no. 4; pp. 1115 - 1124
• Main Authors: PFLUGER, Thomas, SCHMIED, Christoph, PORN, Ute, LEINSINGER, Gerda, VOLLMAR, Christian, DRESEL, Stefan, SCHMID, Irene, HAHN, Klaus
• Format: Journal Article
• Language: English
• Published: Leesburg, VA American Roentgen Ray Society 01.10.2003
• Subjects: Biological and medical sciences; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Iodobenzenes; Magnetic Resonance Imaging; Male; Medical sciences; Neuroblastoma - diagnosis; Neurology; Retrospective Studies; Sensitivity and Specificity; Tumors of the nervous system. Phacomatoses; Radionuclide study; Human; Pediatrics; Nervous system diseases; Malignant tumor; Neuroblastoma; Scintigraphy; Nuclear magnetic resonance imaging; Sensitivity; Specificity; Medical imagery; Diagnosis; Technique; Autonomic neuropathy; Child; Comparative study; Iodine ion

The objectives of this study were to compare MRI and iodine-123 ((123)I) metaiodobenzylguanidine (MIBG) scintigraphy in the detection of neuroblastoma lesions in pediatric patients and to assess the additional value of combined imaging. Fifty MRI and 50 (123)I MIBG examinations (mean interval, 6.4 d...