Falls in PaO2 owing to prostaglandin E1 infusion in an obese patient undergoing laparoscopic cholecystectomy--detection by intra-arterial blood gas monitoring

We monitored the changes of arterial blood gas tensions using a continuous blood gas monitor (Paratrend-7) in an obese patient who underwent laparoscopic cholecystectomy. We could observe continuous changes in PaO2 caused by prostaglandin E1 (PGE1) infusion. Suppression in hypoxic pulmonary vasocons...

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Bibliographic Details
Published inMasui. The Japanese journal of anesthesiology Vol. 46; no. 2; p. 258
Main Authors Koitabashi, T, Sato, N, Takino, Y
Format Journal Article
LanguageJapanese
Published Japan 01.02.1997
Subjects
Adult
Alprostadil - adverse effects
Blood Gas Analysis - instrumentation
Cholecystectomy, Laparoscopic
Female
Humans
Monitoring, Intraoperative
Obesity - physiopathology
Oxygen - blood
Partial Pressure
Vasodilator Agents - adverse effects
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Summary:We monitored the changes of arterial blood gas tensions using a continuous blood gas monitor (Paratrend-7) in an obese patient who underwent laparoscopic cholecystectomy. We could observe continuous changes in PaO2 caused by prostaglandin E1 (PGE1) infusion. Suppression in hypoxic pulmonary vasoconstriction due to PGE1 would lead to falls in PaO2. Intra-arterial blood gas monitoring is quite useful in such a situation in which large .VA/.Q changes are expected due to infusion of PGE1 in an obese patient with high intra-abdominal pressure.
ISSN:0021-4892