Gd43+[AlPCS4]34− Nanoagent Generating 1O2 for Photodynamic Therapy

• Published in: Advanced functional materials Vol. 28; no. 32
• Main Authors: Poß, Marieke, Zittel, Eva, Seidl, Carmen, Meschkov, Anna, Muñoz, Leonel, Schepers, Ute, Feldmann, Claus
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc 08.08.2018
• Subjects: aluminium(III) chlorido phthalocyanine tetrasulfonate; Aluminum; angiogenesis; Biocompatibility; Emission analysis; Emission spectra; gadolinium; In vivo methods and tests; inorganic–organic hybrid nanoparticles; Larvae; Light; Materials science; Nanoparticles; Photodynamic therapy; photosensitizers; Singlet oxygen; Toxicity; Viability; Zebrafish

Gd43+[AlPCS4]34− (AlPCS4: aluminium(III) chlorido phthalocyanine tetrasulfonate) inorganic–organic hybrid nanoparticles (IOH‐NPs) are presented as a novel photosensitizer for singlet oxygen (1O2) generation with potential use in localized photodynamic therapy. The saline nanoparticles contain an unp...