Autoantibodies against coagulation factor VIII

• Published in: Ugeskrift for læger Vol. 160; no. 42; p. 6061
• Main Authors: Friis-Hansen, L J, Andersen, N S, Scheibel, E
• Format: Journal Article
• Language: Danish
• Published: Denmark 12.10.1998
• Subjects: Autoantibodies - analysis; Autoantibodies - biosynthesis; Blood Coagulation Disorders - diagnosis; Blood Coagulation Disorders - drug therapy; Blood Coagulation Disorders - immunology; Factor VIII - immunology; Hemorrhage - diagnosis; Hemorrhage - drug therapy; Hemorrhage - immunology; Humans

Autoantibodies towards coagulation factor VIII is a rare disease, incidence 1 pr. 2.5-5 million/year. The symptoms are most often subcutaneous or intramuscular haemorrhages or uncontrollable bleeding after minimal traumas. Screening tests show prolonged activated partial thromboplastin time, normal...