Modelling the emergence of whisker barrels

• Published in: bioRxiv
• Main Authors: James, Sebastian S, Krubitzer, Leah A, Wilson, Stuart P
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Cold Spring Harbor Laboratory Press 29.01.2020
• Subjects: Brain mapping; Brain stem; Cortex (somatosensory); Gene expression; Gene mapping; Pattern formation; Thalamus

Brain development relies on an interplay between genetic specification and self-organization. Striking examples of this relationship can be found in the somatosensory brainstem, thalamus, and cortex of rats and mice, where the arrangement of the facial whiskers is preserved in the arrangement of cel...