Metformin Alleviates Sepsis-associated Myocardial Injury by Enhancing AMPK/mTOR Signaling Pathway-mediated Autophagy

• Published in: Journal of cardiovascular pharmacology
• Main Authors: Gao, Yu, Liu, Jiao, Li, Kemin, Li, Tian, Li, Ruihan, Zhang, Wenlong, Zhang, Xuanping, Wang, Yan, Chen, Min, Shi, Ruizan, Cao, Jing
• Format: Journal Article
• Language: English
• Published: United States 27.07.2023

Sepsis-associated myocardial injury is one of the main causes of death in intensive care units, and current clinical treatments have not been satisfactory. Therefore, finding an effective intervention is an urgent requirement. Metformin, an anti-type 2 diabetes drug, has been reported to be an autop...