Protective Effect of Silymarin on Erythrocyte Haemolysate Against Benzo(a)Pyrene and Exogenous Reactive Oxygen Species (H sub(2)O sub(2)) Induced Oxidative Stress

• Published in: Chemosphere (Oxford) Vol. 68; no. 8; p. 1511
• Main Authors: Kiruthiga, P V, Shafreen, RBeema, Pandian, SKarutha, Arun, S, Govindu, S, Devi, KPandima
• Format: Journal Article
• Language: English
• Published: 01.07.2007

The in vitro antioxidant properties and protective effects of silymarin in human erythrocyte haemolysates against benzo(a)pyrene [B(a)P], a potent carcinogenic chemical, were examined. It was observed that specific activity of antioxidant enzymes was significantly decreased and the malondialdehyde l...