Quantitative Live Imaging of Human Embryonic Stem Cell Derived Neural Rosettes Reveals Structure-Function Dynamics Coupled to Cortical Development e1004453

• Published in: PLoS computational biology Vol. 11; no. 10
• Main Authors: Ziv, Omer, Zaritsky, Assaf, Yaffe, Yakey, Mutukula, Naresh, Edri, Reuven, Elkabetz, Yechiel
• Format: Journal Article
• Language: English
• Published: San Francisco Public Library of Science 01.10.2015
• Subjects: Annotations; Brain research; Cell division; Nervous system; Stem cells; Transplants & implants

Neural stem cells (NSCs) are progenitor cells for brain development, where cellular spatial composition (cytoarchitecture) and dynamics are hypothesized to be linked to critical NSC capabilities. However, understanding cytoarchitectural dynamics of this process has been limited by the difficulty to...