Prolonged Influenza Virus Shedding and Emergence of Antiviral Resistance in Immunocompromised Patients and Ferrets e1003343

• Published in: PLoS pathogens Vol. 9; no. 5
• Main Authors: Vries, Erhard vander, Stittelaar, Koert J, Amerongen, Geert van, Kroeze, J BVeldhuis, Waal, Leon de, Fraaij, Pieter LA, Meesters, Roland J, Luider, Theo M, Nagel, Bart vander, Koch, Birgit, Vulto, Arnold G, Schutten, Martin, Osterhaus, D ME
• Format: Journal Article
• Language: English
• Published: San Francisco Public Library of Science 01.05.2013
• Subjects: Animals; Hospitalization; Infections; Influenza A virus; Medical research; Mortality; Mustela; Patients; Swine flu; Viruses

Immunocompromised individuals tend to suffer from influenza longer with more serious complications than otherwise healthy patients. Little is known about the impact of prolonged infection and the efficacy of antiviral therapy in these patients. Among all 189 influenza A virus infected immunocompromi...