再次肝切除术与射频消融治疗亚洲复发性肝细胞癌患者效果比较的Meta分析
目的 使用Meta分析的方法比较再次肝切除术与射频消融治疗亚洲复发性肝癌患者的安全性与疗效。 方法 系统检索PubMed、中国知网和万方数据库，日期自建库截止至2020年6月15日。由两位评价者独立检索并提取数据，采用RevMan 5.4.1软件进行Meta分析。 结果 共2项随机对照试验和18项回顾性队列研究符合纳入标准，均来自亚洲国家，包含2903例复发性肝癌患者。再次肝切除术组和射频消融组患者围手术期病死率分别为2%和0，围手术期并发症发生率分别为22.4%和3.3%。再次肝切除术组和射频消融组患者术后1、3、5年总生存率分别为92.3%、66.3%、51.1%和91.4%、69.2%、...
Saved in:
| Published in | Linchuang gandanbing zazhi Vol. 37; no. 5; pp. 1103 - 1109 |
|---|---|
| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | Chinese |
| Published |
Changchun
Journal of Clinical Hepatology
01.01.2021
广西医科大学附属肿瘤医院肝胆外科,广西肝癌诊疗工程技术研究中心,南宁530021 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1001-5256 2097-3497 |
| DOI | 10.3969/j.issn.1001-5256.2021.05.025 |
Cover
| Abstract | 目的 使用Meta分析的方法比较再次肝切除术与射频消融治疗亚洲复发性肝癌患者的安全性与疗效。 方法 系统检索PubMed、中国知网和万方数据库，日期自建库截止至2020年6月15日。由两位评价者独立检索并提取数据，采用RevMan 5.4.1软件进行Meta分析。 结果 共2项随机对照试验和18项回顾性队列研究符合纳入标准，均来自亚洲国家，包含2903例复发性肝癌患者。再次肝切除术组和射频消融组患者围手术期病死率分别为2%和0，围手术期并发症发生率分别为22.4%和3.3%。再次肝切除术组和射频消融组患者术后1、3、5年总生存率分别为92.3%、66.3%、51.1%和91.4%、69.2%、39.9%。两组患者术后1、3、5年无瘤生存率分别为67.9%、48.3%、34.4%和57.5%、27.9%、14.0%。Meta分析结果提示，两组患者的总生存率差异无统计学意义(HR=0.89，95%CI：0.77~1.02，P=0.10)，但再次肝切除术组患者的无瘤生存率显著高于射频消融组(HR=0.79，95%CI：0.72~0.87，P＜0.001)。 结论 目前证据显示，再次肝切除术治疗复发性肝癌有更高的无瘤生存率，但两组患者的总生存率相似。 |
|---|---|
| AbstractList | 目的 使用Meta分析的方法比较再次肝切除术与射频消融治疗亚洲复发性肝癌患者的安全性与疗效。 方法 系统检索PubMed、中国知网和万方数据库，日期自建库截止至2020年6月15日。由两位评价者独立检索并提取数据，采用RevMan 5.4.1软件进行Meta分析。 结果 共2项随机对照试验和18项回顾性队列研究符合纳入标准，均来自亚洲国家，包含2903例复发性肝癌患者。再次肝切除术组和射频消融组患者围手术期病死率分别为2%和0，围手术期并发症发生率分别为22.4%和3.3%。再次肝切除术组和射频消融组患者术后1、3、5年总生存率分别为92.3%、66.3%、51.1%和91.4%、69.2%、39.9%。两组患者术后1、3、5年无瘤生存率分别为67.9%、48.3%、34.4%和57.5%、27.9%、14.0%。Meta分析结果提示，两组患者的总生存率差异无统计学意义(HR=0.89，95%CI：0.77~1.02，P=0.10)，但再次肝切除术组患者的无瘤生存率显著高于射频消融组(HR=0.79，95%CI：0.72~0.87，P＜0.001)。 结论 目前证据显示，再次肝切除术治疗复发性肝癌有更高的无瘤生存率，但两组患者的总生存率相似。 R735.7; 目的 使用Meta分析的方法比较再次肝切除术与射频消融治疗亚洲复发性肝癌患者的安全性与疗效.方法 系统检索PubMed、中国知网和万方数据库,日期自建库截止至2020年6月15日.由两位评价者独立检索并提取数据,采用RevMan 5.4.1软件进行Meta分析.结果 共2项随机对照试验和18项回顾性队列研究符合纳入标准,均来自亚洲国家,包含2903例复发性肝癌患者.再次肝切除术组和射频消融组患者围手术期病死率分别为2％和0,围手术期并发症发生率分别为22.4％和3.3％.再次肝切除术组和射频消融组患者术后1、3、5年总生存率分别为92.3％、66.3％、51.1％和91.4％、69.2％、39.9％.两组患者术后1、3、5年无瘤生存率分别为67.9％、48.3％、34.4％和57.5％、27.9％、14.0％.Meta分析结果提示,两组患者的总生存率差异无统计学意义(HR=0.89,95％CI:0.77～1.02,P=0.10),但再次肝切除术组患者的无瘤生存率显著高于射频消融组(HR=0.79,95％CI:0.72～0.87,P<0.001).结论 目前证据显示,再次肝切除术治疗复发性肝癌有更高的无瘤生存率,但两组患者的总生存率相似. |
| Author | 李旻骏 刘昊天 钟鉴宏 黎乐群 邓柱鉴 滕煜宪 梁秀妹 霍荣瑞 向邦德 |
| AuthorAffiliation | 广西医科大学附属肿瘤医院肝胆外科,广西肝癌诊疗工程技术研究中心,南宁530021 |
| AuthorAffiliation_xml | – name: 广西医科大学附属肿瘤医院肝胆外科,广西肝癌诊疗工程技术研究中心,南宁530021 |
| Author_FL | HUO Rongrui TENG Yuxian LIANG Xiumei LI Lequn LI Minjun ZHONG Jianhong XIANG Bangde DENG Zhujian LIU Haotian |
| Author_FL_xml | – sequence: 1 fullname: LI Minjun – sequence: 2 fullname: DENG Zhujian – sequence: 3 fullname: LIU Haotian – sequence: 4 fullname: TENG Yuxian – sequence: 5 fullname: HUO Rongrui – sequence: 6 fullname: LIANG Xiumei – sequence: 7 fullname: XIANG Bangde – sequence: 8 fullname: LI Lequn – sequence: 9 fullname: ZHONG Jianhong |
| Author_xml | – sequence: 1 fullname: 李旻骏 – sequence: 2 fullname: 邓柱鉴 – sequence: 3 fullname: 刘昊天 – sequence: 4 fullname: 滕煜宪 – sequence: 5 fullname: 霍荣瑞 – sequence: 6 fullname: 梁秀妹 – sequence: 7 fullname: 向邦德 – sequence: 8 fullname: 黎乐群 – sequence: 9 fullname: 钟鉴宏 |
| BookMark | eNpF0M1KAlEUB_BLFGTmU9SizUxn7jj3zl2G9AVGG_cyM86IIqM5SuBK1GwWWQl9oJhQCW0CQyIioadxruNbNGIUZ3HO4sc5h_8aWrbztonQpgSizAjbzooZx7FFCUASFKwQEQOWRFBEwMoSCmFgVJCjjC6j0J9ZRRHHyeigSDJhUYWEkOY1W_z10a89eO75rDPgveHk89J7a8ye2vzD9fstPhpP7-4nX13-PvIGLe-qzasvgZ-Om369P-1c8NqzXz3jty7v9_jwxv-uT7uNI7OkeW6T96_X0Yql5Rwz8tvDKLG3m4gdCPHj_cPYTlwoEIkIKVXVGRAVWMpMqSbDigXzWaI4-JUGRSyVGmAxWTMMMExLB10jhEqU6hpYchhtLdaearal2elkNl8u2sHBZM5Ip_RKZR4PKIBJQDcWtFDMn5RNp_RvZSwzSqIEq_IPpa2JAA |
| ClassificationCodes | R735.7 |
| ContentType | Journal Article |
| Copyright | 2021. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
| Copyright_xml | – notice: 2021. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
| DBID | 3V. 7X7 7XB 88E 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH K9. M0S M1P PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI 2B. 4A8 92I 93N PSX TCJ |
| DOI | 10.3969/j.issn.1001-5256.2021.05.025 |
| DatabaseName | ProQuest Central (Corporate) Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Central ProQuest One Community College ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Health & Medical Complete (Alumni) Health & Medical Collection (Alumni) Medical Database ProQuest Central Premium ProQuest One Academic (New) Publicly Available Content Database (Proquest) ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition Wanfang Data Journals - Hong Kong WANFANG Data Centre Wanfang Data Journals 万方数据期刊 - 香港版 China Online Journals (COJ) China Online Journals (COJ) |
| DatabaseTitle | Publicly Available Content Database ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Central ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Health & Medical Research Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) |
| DatabaseTitleList | Publicly Available Content Database |
| Database_xml | – sequence: 1 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| DocumentTitle_FL | Clinical effect of re-hepatic resection versus radiofrequency ablation in treatment of recurrent hepatocellular carci- noma in Asia:A Meta-analysis |
| EISSN | 2097-3497 |
| EndPage | 1109 |
| ExternalDocumentID | lcgdbzz202105026 |
| GeographicLocations | Asia |
| GeographicLocations_xml | – name: Asia |
| GrantInformation_xml | – fundername: (国家自然科学基金); (广西自然科学基金); ("广西八桂学者"专项经费); (中国博士后科学基金); 广西高等学校高水平创新团队及卓越学者计划 funderid: (国家自然科学基金); (广西自然科学基金); ("广西八桂学者"专项经费); (中国博士后科学基金); 广西高等学校高水平创新团队及卓越学者计划 |
| GroupedDBID | -05 3V. 5XA 5XF 7X7 7XB 88E 8FI 8FJ 8FK 92F 92I ABDBF ABJNI ABUWG ACGFS ACUHS AFKRA ALMA_UNASSIGNED_HOLDINGS AZQEC BENPR CCEZO CCPQU CIEJG CW9 DWQXO EAD EAP EOJEC ESX FYUFA K9. M1P OBODZ OK1 PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI RNS TCJ TGQ U1G U5O 2B. 4A8 93N IPNFZ PSX RIG |
| ID | FETCH-LOGICAL-p616-d88b906809ded8e925f009de17213676766f87c0f93acc0cefb0ba667177ba0f3 |
| IEDL.DBID | 7X7 |
| ISSN | 1001-5256 |
| IngestDate | Thu May 29 04:06:09 EDT 2025 Sat Aug 23 12:56:27 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 5 |
| Keywords | 肝切除术 Meta分析(主题) 射频消融 癌,肝细胞 |
| Language | Chinese |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-p616-d88b906809ded8e925f009de17213676766f87c0f93acc0cefb0ba667177ba0f3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 |
| OpenAccessLink | https://www.proquest.com/docview/3239764628?pq-origsite=%requestingapplication% |
| PQID | 3239764628 |
| PQPubID | 7350069 |
| PageCount | 7 |
| ParticipantIDs | wanfang_journals_lcgdbzz202105026 proquest_journals_3239764628 |
| PublicationCentury | 2000 |
| PublicationDate | 20210101 2021 |
| PublicationDateYYYYMMDD | 2021-01-01 |
| PublicationDate_xml | – month: 01 year: 2021 text: 20210101 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | Changchun |
| PublicationPlace_xml | – name: Changchun |
| PublicationTitle | Linchuang gandanbing zazhi |
| PublicationTitle_FL | Journal of Clinical Hepatology |
| PublicationYear | 2021 |
| Publisher | Journal of Clinical Hepatology 广西医科大学附属肿瘤医院肝胆外科,广西肝癌诊疗工程技术研究中心,南宁530021 |
| Publisher_xml | – name: Journal of Clinical Hepatology – name: 广西医科大学附属肿瘤医院肝胆外科,广西肝癌诊疗工程技术研究中心,南宁530021 |
| SSID | ssib051369456 ssib061082477 ssj0041983 ssib001103858 ssib053243598 ssib002264326 ssib038074677 |
| Score | 2.2230787 |
| Snippet | 目的 使用Meta分析的方法比较再次肝切除术与射频消融治疗亚洲复发性肝癌患者的安全性与疗效。 方法 系统检索PubMed、中国知网和万方数据库，日期自建库截止至2020年6月15日。由两位评价者独立检索并提取数据，采用RevMan 5.4.1软件进行Meta分析。 结果... R735.7; 目的 使用Meta分析的方法比较再次肝切除术与射频消融治疗亚洲复发性肝癌患者的安全性与疗效.方法 系统检索PubMed、中国知网和万方数据库,日期自建库截止至2020年6月15日.由两位评价者独立检索并提取数据,采用RevMan 5.4.1软件进行Meta分析.结果... |
| SourceID | wanfang proquest |
| SourceType | Aggregation Database |
| StartPage | 1103 |
| SubjectTerms | Ablation Liver cancer Meta-analysis |
| Title | 再次肝切除术与射频消融治疗亚洲复发性肝细胞癌患者效果比较的Meta分析 |
| URI | https://www.proquest.com/docview/3239764628 https://d.wanfangdata.com.cn/periodical/lcgdbzz202105026 |
| Volume | 37 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQMTE2Sk1OMkzVNUs0MNc1SU5M1k0CNvV1Dc3M00zMEpNTDVJBG5x9_cw8Qk28IkwjoANuxdBllbAyEVxQp-Qng8bI9Y2NQDUnaCelfUGhLujWKNDsKvQKDWYGVvDRZcD0bB6BqE4NDQ1QzmoBbRpFaq6Azlo3QTrOzdTQ2MzSBHG2jCmwsQE64A7GB7Y0LIzA-zYhJb0JsMMOWcAP7JKbAtsOHAwqoF6wpZmlfhY4D-vBpYA9USND8BmhRqYojVn28sS8tMS8dKRazU2QgR_aHFVwhKQfIQamqgxhBg5f6IS7CEPi07beZ2sWvmia-7Sj_eXMJc_mrH-yo-_phpaXiyY-29bxYl7vs027n0-b_mTXrGdbNj1d0vu0f-KzhuVA9c93t71onvd8Zs-zpsUvGlqfTe14Nm_Os_VTXuxrfj6rxTe1JPFpR9uzeRNEGULcXEOcPXShtzLoFpgZmummWFgkWYIu7LBMSU2xSLU0Mk0zALFBXUnw6W9mZmkW5skGaZbGicnJBsmpaUkGSYlmZsBuo3lSokGasRgDS15-XqoEg4KFeUqqqUWKmbFJsrFJKtBYoLR5apI5qJRIMzY3kmSQgYVTPDRnFccj0oEkgyI07BCyOcnpKUlVVaDANjAFpjkp_EZIM3CBlEKGVGQYWEqKSlNlgY2MkiQ5cEqSY2B1dHJxcgPSTq5-AUEAOQzm_A |
| linkProvider | ProQuest |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQMTE2Sk1OMkzVNUs0MNc1SU5M1k0CNvV1Dc3M00zMEpNTDVJBG5x9_cw8Qk28IkwjmBjWwvbCgJZVwspEcEGdkp8MGiPXNzYC1ZygnZT2BYW6oFujQLOrsCs0IMnCO7WyHNhlK7b1dAHGr6qRkZtriLOHLvRWAd0CM0Mz3RQLiyRL0IUTlimpKRaplkamaQYgNqgrBD69zMwszcI82SDN0jgxOdkgOTUtySAp0cwM2O0xT0o0SDMGGsvMwGoC2tDKwsDq5OoXEIRofxgaoBwOA9qlitQ-Ah3uboJ0fpwp0EZLE8RhNqbA1g3oRD0YH9i0sTACbxSFVC0mhpYWkB0DBobAHqSpGQeDCqjbbWlmqZ8FLjT04FLArq-RIfhQUiNTlNYze3liXlpiXjpSNeomyMAPbf8qOEISrBADU1WGMAOHL3SGX4Qh8Wlb77M1C180zX3a0f5y5pJnc9Y_2dH3dEPLy0UTn23reDGv99mm3c-nTX-ya9azLZueLul92j_xWcNyoPrnu9teNM97PrPnWdPiFw2tz6Z2PJs359n6KS_2NT-f1eKbWpL4tKPt2bwJogwhtIgwMQaWvPy8VAkGBQvzlFRTixQzY5NkY5NUoLFAafPUJHNQsZRmbG4kySADC6d4aFYujkckPEkGRWjYIWRzktNTkqqqQIFtYApM5FL4jZBn4PQI8fWJ9_H085Zm4AJpg4znyDCwlBSVpsoCWzglSXLQdKXAEE_jlAwAMqshcg |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E5%86%8D%E6%AC%A1%E8%82%9D%E5%88%87%E9%99%A4%E6%9C%AF%E4%B8%8E%E5%B0%84%E9%A2%91%E6%B6%88%E8%9E%8D%E6%B2%BB%E7%96%97%E4%BA%9A%E6%B4%B2%E5%A4%8D%E5%8F%91%E6%80%A7%E8%82%9D%E7%BB%86%E8%83%9E%E7%99%8C%E6%82%A3%E8%80%85%E6%95%88%E6%9E%9C%E6%AF%94%E8%BE%83%E7%9A%84Meta%E5%88%86%E6%9E%90&rft.jtitle=%E4%B8%B4%E5%BA%8A%E8%82%9D%E8%83%86%E7%97%85%E6%9D%82%E5%BF%97&rft.au=%E6%9D%8E%E6%97%BB%E9%AA%8F&rft.au=%E9%82%93%E6%9F%B1%E9%89%B4&rft.au=%E5%88%98%E6%98%8A%E5%A4%A9&rft.au=%E6%BB%95%E7%85%9C%E5%AE%AA&rft.date=2021&rft.pub=%E5%B9%BF%E8%A5%BF%E5%8C%BB%E7%A7%91%E5%A4%A7%E5%AD%A6%E9%99%84%E5%B1%9E%E8%82%BF%E7%98%A4%E5%8C%BB%E9%99%A2%E8%82%9D%E8%83%86%E5%A4%96%E7%A7%91%2C%E5%B9%BF%E8%A5%BF%E8%82%9D%E7%99%8C%E8%AF%8A%E7%96%97%E5%B7%A5%E7%A8%8B%E6%8A%80%E6%9C%AF%E7%A0%94%E7%A9%B6%E4%B8%AD%E5%BF%83%2C%E5%8D%97%E5%AE%81530021&rft.issn=1001-5256&rft.volume=37&rft.issue=5&rft.spage=1103&rft.epage=1109&rft_id=info:doi/10.3969%2Fj.issn.1001-5256.2021.05.025&rft.externalDocID=lcgdbzz202105026 |
| thumbnail_s | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fwww.wanfangdata.com.cn%2Fimages%2FPeriodicalImages%2Flcgdbzz%2Flcgdbzz.jpg |