熊果酸对TGF-β1诱导肝细胞凋亡的抑制作用及其机制

• Published in: Jie fang jun yi xue za zhi Vol. 42; no. 5; pp. 383 - 388
• Main Authors: Juan-juan, ZHOU, Wen-hua, HE, Da-kai, GAN, ZHANG, Wang, A-ping, PENG, An-jiang, WANG, Bi-min, LI, ZHU, Xuan
• Format: Journal Article
• Language: Chinese
• Published: Beijing People's Military Medical Press 01.01.2017; 330006,南昌 南昌大学第一附属医院消化内科
• Subjects: Apoptosis; Liver; Rodents; 细胞凋亡; 熊果酸; transforming growth factor β1; NADPH oxidase; 肝细胞; apoptosis; NADPH氧化酶; hepatocytes; 转化生长因子β1; ursolic acid

Objective To study the effect of ursolic acid (UA) intervention on hepatocyte apoptosis induced by TGF-β1 and its potential mechanism. Methods Primary hepatocytes were extracted from healthy SD rats by in situ perfusion, cultured for 12-24h, then randomly divided into the following groups: blank con...