The Pseudomonas aeruginosa Type III Translocon Is Required for Biofilm Formation at the Epithelial Barrier e1004479

• Published in: PLoS pathogens Vol. 10; no. 11
• Main Authors: Tran, Cindy S, Rangel, Stephanie M, Almblad, Henrik, Kierbel, Arlinet, Givskov, Michael, Tolker-Nielsen, Tim, Hauser, Alan R, Engel, Joanne N
• Format: Journal Article
• Language: English
• Published: San Francisco Public Library of Science 01.11.2014
• Subjects: Aggregates; Antibiotic resistance; Antibiotics; Bacteria; Bacterial infections; Bacteriology; Biofilms; Cystic fibrosis; Experiments; Extracellular matrix; Infections; Membrane filters; Microscopy; Pneumonia; Pseudomonas aeruginosa; Statistical analysis; Toxins

Clinical infections by Pseudomonas aeruginosa, a deadly Gram-negative, opportunistic pathogen of immunocompromised hosts, often involve the formation of antibiotic-resistant biofilms. Although biofilm formation has been extensively studied in vitro on glass or plastic surfaces, much less is known ab...