Hsp70 Isoforms Are Essential for the Formation of Kaposi's Sarcoma-Associated Herpesvirus Replication and Transcription Compartments e1005274

• Published in: PLoS pathogens Vol. 11; no. 11
• Main Authors: Baquero-Pérez, Belinda, Whitehouse, Adrian
• Format: Journal Article
• Language: English
• Published: San Francisco Public Library of Science 01.11.2015
• Subjects: Cancer; Cell cycle; Clinical trials; Colleges & universities; Cytoplasm; Cytotoxicity; Deoxyribonucleic acid; DNA; Genes; Human herpesvirus 8; Kaposi's sarcoma-associated herpesvirus; Kaposis sarcoma; Labeling; Medical research; Molecular weight; Proteomics; RNA polymerase; Viral infections; Viruses

Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic herpesvirus associated with various AIDS-related malignancies. Like other herpesviruses, multiple processes required for KSHV lytic replication, including viral transcription, viral DNA synthesis and capsid assembly occur in virus-i...