关注慢性乙型肝炎特殊人群抗病毒治疗时机及治疗策略
慢性乙型肝炎 (CHB) 特殊人群要充分衡量肝硬化和肝癌家族史、年龄、疾病分期和抗病毒疗效等因素。CHB特殊人群选择合适抗病毒治疗时机并及时调整抗病毒策略，对于延缓疾病进展和降低肝硬化及肝细胞癌的发生起到重要的作用。本文将针对年龄≤30岁且ALT水平正常慢性HBV感染者、年龄>30岁且ALT水平正常慢性HBV感染孕妇、慢性HBV感染者儿童和HBeAg阳性低病毒血症经治CHB患者等特殊人群的抗病毒治疗时机和治疗策略进行阐述，帮助临床医生对CHB特殊人群选择更好的抗病毒治疗时机和优化治疗策略。...
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| Published in | Linchuang gandanbing zazhi Vol. 40; no. 5; pp. 861 - 865 |
|---|---|
| Main Authors | , |
| Format | Journal Article |
| Language | Chinese |
| Published |
Changchun
Journal of Clinical Hepatology
01.01.2024
中国医科大学附属盛京医院感染科,沈阳 110022 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1001-5256 2097-3497 |
| DOI | 10.12449/JCH240502 |
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| Abstract | 慢性乙型肝炎 (CHB) 特殊人群要充分衡量肝硬化和肝癌家族史、年龄、疾病分期和抗病毒疗效等因素。CHB特殊人群选择合适抗病毒治疗时机并及时调整抗病毒策略，对于延缓疾病进展和降低肝硬化及肝细胞癌的发生起到重要的作用。本文将针对年龄≤30岁且ALT水平正常慢性HBV感染者、年龄>30岁且ALT水平正常慢性HBV感染孕妇、慢性HBV感染者儿童和HBeAg阳性低病毒血症经治CHB患者等特殊人群的抗病毒治疗时机和治疗策略进行阐述，帮助临床医生对CHB特殊人群选择更好的抗病毒治疗时机和优化治疗策略。 |
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| AbstractList | 慢性乙型肝炎(CHB)特殊人群要充分衡量肝硬化和肝癌家族史、年龄、疾病分期和抗病毒疗效等因素.CHB特殊人群选择合适抗病毒治疗时机并及时调整抗病毒策略,对于延缓疾病进展和降低肝硬化及肝细胞癌的发生起到重要的作用.本文将针对年龄≤30岁且ALT水平正常慢性HBV感染者、年龄>30岁且ALT水平正常慢性HBV感染孕妇、慢性HBV感染者儿童和HBeAg阳性低病毒血症经治CHB患者等特殊人群的抗病毒治疗时机和治疗策略进行阐述,帮助临床医生对CHB特殊人群选择更好的抗病毒治疗时机和优化治疗策略. 慢性乙型肝炎 (CHB) 特殊人群要充分衡量肝硬化和肝癌家族史、年龄、疾病分期和抗病毒疗效等因素。CHB特殊人群选择合适抗病毒治疗时机并及时调整抗病毒策略，对于延缓疾病进展和降低肝硬化及肝细胞癌的发生起到重要的作用。本文将针对年龄≤30岁且ALT水平正常慢性HBV感染者、年龄>30岁且ALT水平正常慢性HBV感染孕妇、慢性HBV感染者儿童和HBeAg阳性低病毒血症经治CHB患者等特殊人群的抗病毒治疗时机和治疗策略进行阐述，帮助临床医生对CHB特殊人群选择更好的抗病毒治疗时机和优化治疗策略。 |
| Abstract_FL | Several factors need to be considered for special populations with chronic hepatitis B(CHB),such as the family history of liver cirrhosis and liver cancer,age,disease stage,and antiviral response.It is necessary to select the appropriate timing of antiviral therapy and timely adjust antiviral strategies for CHB populations,which plays an important role in delaying disease progression and reducing the development of liver cirrhosis and hepatocellular carcinoma.This article elaborates on the timing and strategies for antiviral therapy in the special populations such as patients with chronic HBV infection who have an age of≤30 years and a normal alanine aminotransferase(ALT)level,pregnant women with chronic HBV infection who have an age of>30 years and a normal ALT level,children with chronic HBV infection,and treatment-experienced HBeAg-positive CHB patients with low-level viremia,so as to help clinicians choose a better timing of antiviral therapy and optimize the strategies of antiviral therapy for special CHB populations. |
| Author | 窦晓光 丁洋 |
| AuthorAffiliation | 中国医科大学附属盛京医院感染科,沈阳 110022 |
| AuthorAffiliation_xml | – name: 中国医科大学附属盛京医院感染科,沈阳 110022 |
| Author_FL | DOU Xiaoguang DING Yang |
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| Author_xml | – sequence: 1 fullname: 丁洋 – sequence: 2 fullname: 窦晓光 |
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| Keywords | Hepatitis B,Chronic Special Population 治疗学 特殊人群 乙型肝炎,慢性 Therapeutics |
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| SubjectTerms | Hepatitis B Infections Liver cancer Liver cirrhosis |
| Title | 关注慢性乙型肝炎特殊人群抗病毒治疗时机及治疗策略 |
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