Optical recording of action potential initiation and propagation in mouse skeletal muscle fibers

• Published in: bioRxiv
• Main Authors: Banks, Quinton, Pratt, Stephen Joseph Paul, Shama Rajan Iyer, Lovering, Richard Michael, Erick Hern ndez-Ochoa, Schneider, Martin F
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Cold Spring Harbor Laboratory Press 31.03.2018
• Subjects: Action potential; Calcium (intracellular); Musculoskeletal system; Propagation; Skeletal muscle; Sodium; Tetrodotoxin; Velocity

Individual skeletal muscle fibers have been used to examine a wide variety of cellular functions and pathologies. Among other parameters, skeletal muscle action potential propagation has been measured to assess the integrity and function of skeletal muscle. In this paper, we utilize Di-8-ANEPPS, a p...